Výsledky vyhledávání - "O. G. Kulakova"

Akademický článek

Global transcriptome profiling of blood mononuclear cells from individuals with radiologically isolated syndrome reveals abnormalities characteristic of the rapid manifestation of multiple sclerosis symptoms

Autor: M. S. Kozin, A. R. Kabaeva, M. A. Omarova, A. N. Boyko, O. O. Favorova, O. G. Kulakova

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 0, Pp 31-37 (2024)

Objective: to look for differences in the transcriptome profiles in mononuclear blood cells of a group of patients with radiologically isolated syndrome (RIS) who developed symptoms of multiple sclerosis (MS) in the following three years of observati

Externí odkaz: https://doaj.org/article/6bdaa64ad8d5454b8e560ec2c05dfa07

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Akademický článek

MicroRNAs as biomarkers of multiple sclerosis progression

Autor: N. M. Baulina, I. S. Kiselev, O. G. Kulakova, E. V. Popova, O. O. Favorova, A. N. Boyko

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 15, Iss 0, Pp 4-7 (2023)

Multiple sclerosis (MS) is an autoimmune inflammatory neurodegenerative disease of the central nervous system. The disease is characterized by a heterogeneous clinical course, which is reflected in the fact that there are various types, such as relap

Externí odkaz: https://doaj.org/article/6c07ed75f7ed4b208a4bb6dbd46eea88

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Akademický článek

Reduced expression of the tumor necrosis factor gene in blood mononuclear cells in radiologically isolated syndrome – validation of transcriptome analysis results

Autor: M. S. Kozin, N. M. Baulina, I. S. Kiselev, A. R. Kabaeva, A. N. Boyko, O. O. Favorova, O. G. Kulakova

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 14, Iss 1S, Pp 16-20 (2022)

Radiologically isolated syndrome (RIS) is a nosological form in which magnetic resonance imaging (MRI) reveals lesions of the white matter of the brain and/or spinal cord characteristic of multiple sclerosis (MS) in individuals in the absence of clin

Externí odkaz: https://doaj.org/article/06f80ebfb28c49adb4c9ef8ae6c1378c

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Akademický článek

The combined effect of nuclear and mitochondrial genomes on the risk of developing multiple sclerosis

Autor: M. S. Kozin, I. S. Kiselev, A. N. Boyko, O. G. Kulakova, O. O. Favorova

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 12, Iss 1S, Pp 15-19 (2020)

Multiple sclerosis (MS) is a severe chronic CNS disease characterized by autoimmune inflammation, demyelination, and neurodegeneration. The interaction of mitochondrial and nuclear genomes is shown to be important in the formation of a predisposition

Externí odkaz: https://doaj.org/article/6510d07371b54f42adcb06fc9f0cd469

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Akademický článek

Polymorphic variants in the PVT1 locus affect multiple sclerosis severity

Autor: I. S. Kiselev, M. S. Kozin, N. M. Baulina, G. V. Pavlova, A. N. Boyko, O. G. Kulakova, O. O. Favorova

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 12, Iss 1S, Pp 4-8 (2020)

Multiple sclerosis (MS) is a chronic autoimmune disease, in the pathogenesis of which the concurrence of demyelination of central nervous system (CNS) axons and neurodegeneration plays a role and which is accompanied by progressive neurological dysfu

Externí odkaz: https://doaj.org/article/fcfb9645bb0b42aba1e6c92494bb83d4

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Akademický článek

Mitochondrial genome and risk of multiple sclerosis

Autor: A. N. Boyko, M. S. Kozin, G. Zh. Osmak, O. G. Kulakova, O. O. Favorova

Publikováno v: Неврология, нейропсихиатрия, психосоматика, Vol 11, Iss 3, Pp 43-46 (2019)

Mitochondrial DNA (mtDNA) polymorphism makes a certain contribution to the formation of a genetic risk of multiple sclerosis (MS).Objective: to analyze the frequency of mtDNA variants in patients with MS and control individuals in the Russian populat

Externí odkaz: https://doaj.org/article/0ce80cee909d4ed28d771f7110420ed6

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