PROLONGATION OF EXPERIMENTAL DIABETES MELLITUS INCREASED SUSCEPTIBILITY TO REPERFUSION VENTRICULAR TACHYARRHYTHMIAS

Autor: O G Bernikova, M A Vaykshnorayte, Ekaterina Nikolaevna Pershina, Jan E. Azarov, A O Ovechkin

Diabetes mellitus (DM) is associated with increased risk of sudden cardiac death, but its role in arrhythmogenesis is not clear. We evaluated contributions of DM duration and hyperglycemia level to development of proarrhythmic electrophysiological ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd996bd129ef7c68076d84bd8f99065
https://doi.org/10.22541/au.164864256.63059310/v1

Melatonin pretreatment does not modify extrasystolic burden in the rat ischemia-reperfusion model

Autor: A V, Durkina, O G, Bernikova, N J, Mikhaleva, N M, Paderin, K A, Sedova, M A, Gonotkov, V S, Kuzmin, J E, Azarov

Publikováno v: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 72(1)

The mechanism of reentrant ventricular tachyarrhythmias complicating acute myocardial ischemia is largely based on the interaction between an arrhythmogenic substrate and triggers. Melatonin was proposed as an antiarrhythmic medication and was shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::748151417e7396c93ee5a69208988c6c
https://pubmed.ncbi.nlm.nih.gov/34272351

Association between antiarrhythmic, electrophysiological and antioxidative effects of melatonin in ischemia/reperfusion

Autor: Jan E. Azarov, Ekaterina V. Lopatina, O G Bernikova, M A Vaykshnorayte, Alexandra Ivanova, Michael G. Pliss, Emiliano Raúl Diez, Galina A. Kutaeva, Julia I. Cuprova, Ksenia Sedova

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences
Volume 20
Issue 24

Melatonin is assumed to confer cardioprotective action via antioxidative properties. We evaluated the association between ventricular tachycardia and/or ventricular fibrillation (VT/VF) incidence, oxidative stress, and myocardial electrophysiological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1e10cadf79935ded4c2a34207f38e7
https://www.mdpi.com/1422-0067/20/24/6331

Repolarization in perfused myocardium predicts reperfusion ventricular tachyarrhythmias

Autor: Dmitry Shmakov, Jan E. Azarov, O G Bernikova, Ksenia Sedova, Aleksey O. Ovechkin, Natalia V. Arteyeva, S. N. Kharin

Publikováno v: Journal of Electrocardiology. 51:542-548

Aim of the study was to find out which myocardial repolarization parameters predict reperfusion ventricular tachycardia and fibrillation (VT/VF) and determine how these parameters express in ECG.Coronary occlusion and reperfusion (30/30min) was induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f38b15b9198837abfe0de210c3cb07
https://doi.org/10.1016/j.jelectrocard.2017.12.003

ELECTROCARDIOGRAPHIC MARKERS OF CARDIOMYOCYTES’ ACTION POTENTIALS LENGTHENING IN THE BORDER ZONE OF ISCHEMIA (EXPERIMENTAL AND MODEL STUDY)

Autor: Jan E. Azarov, Natalia V. Arteyeva, Ksenia Sedova, O G Bernikova

Publikováno v: Translational Medicine. 4:71-77

Background : Ventricular fibrillation within the first 5 min of reperfusion was observed in the animals with lengthening but not shortening of action potential duration (APD) in the border zone of ischemia. Objective : The objective of the study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c78687aa335174fe5a41383531a7c260
https://doi.org/10.18705/2311-4495-2017-4-2-71-77