Zobrazeno 1 - 10
of 125
pro vyhledávání: '"O. Forsberg"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Cryo electron microscopy (cryo-EM) is used by biological research to visualize biomolecular complexes in 3D, but the heterogeneity of cryo-EM reconstructions is not easily estimated. Current processing paradigms nevertheless exert great effo
Externí odkaz:
https://doaj.org/article/68f9eef138814e649491e4b4f49f129d
Autor:
Bjoern O. Forsberg
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The pyruvate dehydrogenase complex (PDC) is a central metabolic enzyme in all living cells composed majorly of E1, E2, and E3. Tight coupling of their reactions makes each component essential, so that any loss impacts oxidative metabolism pa
Externí odkaz:
https://doaj.org/article/3b86c3eb4f3748488186b41786f73150
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it
Externí odkaz:
https://doaj.org/article/ef295762d5314830a67e8da8137ed4f0
Publikováno v:
IUCrJ, Vol 4, Iss 6, Pp 723-727 (2017)
The introduction of direct detectors and the automation of data collection in cryo-EM have led to a surge in data, creating new opportunities for advancing computational processing. In particular, on-the-fly workflows that connect data collection wit
Externí odkaz:
https://doaj.org/article/9ac30ee046bb42b0bb374c25ac6bd725
Autor:
Jasenko Zivanov, Takanori Nakane, Björn O Forsberg, Dari Kimanius, Wim JH Hagen, Erik Lindahl, Sjors HW Scheres
Publikováno v:
eLife, Vol 7 (2018)
Here, we describe the third major release of RELION. CPU-based vector acceleration has been added in addition to GPU support, which provides flexibility in use of resources and avoids memory limitations. Reference-free autopicking with Laplacian-of-G
Externí odkaz:
https://doaj.org/article/75a3cbbc12fd49f7b6239eb7c778a385
Akademický článek
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Autor:
Pranav N.M. Shah, James B. Gilchrist, Björn O. Forsberg, Alister Burt, Andrew Howe, Shyamal Mosalaganti, William Wan, Julika Radecke, Yuriy Chaban, Geoff Sutton, David I. Stuart, Mark Boyce
Publikováno v:
Cell Host & Microbe. 31:604-615.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adc7befdec20e0e6a58655db07b163c1
https://doi.org/10.1016/j.chom.2023.03.004
https://doi.org/10.1016/j.chom.2023.03.004
Publikováno v:
eLife, Vol 5 (2016)
By reaching near-atomic resolution for a wide range of specimens, single-particle cryo-EM structure determination is transforming structural biology. However, the necessary calculations come at large computational costs, which has introduced a bottle
Externí odkaz:
https://doaj.org/article/1431a1ad2d13425b881afbedce1a6fa5
Autor:
Urska Rovsnik, Björn O. Forsberg, Linnea Yvonnesdotter, Rebecca J. Howard, Yuxuan Zhuang, Marta Carroni, Erik Lindahl
Publikováno v:
Life Science Alliance
Cryo-EM structures and molecular simulations of a pentameric ligand-gated ion channel, GLIC, in resting and activating conditions implicate protonation sites and altered dynamics in sequential gating.
Ligand-gated ion channels are critical media
Ligand-gated ion channels are critical media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e849371350bf1bec49e4319280c89e5
http://europepmc.org/articles/PMC8326787
http://europepmc.org/articles/PMC8326787
Autor:
F Bello, M Lördal, F Johansson, H Sabhan, S Muhsen, A Borin, O Forsberg, C Wennerström, C Söderman, S Almer
Publikováno v:
Journal of Crohn's and Colitis. 16:i130-i131
Background Ustekinumab (UST), an anti-interleukin-12/23 antibody, has successfully been introduced in the treatment of IBD, mainly in patients failing anti-TNF-agents. The STOCUSTE study includes IBD patients treated with UST at four teaching hospita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5bf233b2859b1439f37424e0d953521
https://doi.org/10.1093/ecco-jcc/jjab232.127
https://doi.org/10.1093/ecco-jcc/jjab232.127