Zobrazeno 1 - 10
of 10
pro vyhledávání: '"O. E. Klementyeva"'
Autor:
O. E. Klementyeva, A. V. Smirnova, N. Yu. Kulbachevskaya, E. Yu. Grigorieva, Yu. S. Lagodzinskaya, T. G. Gevorkyan
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 3, Pp 251-264 (2024)
INTRODUCTION. Currently in the Russian Federation and the Eurasian Economic Union (EAEU), the conduct of non-clinical studies of radiopharmaceuticals is regulated by general guidelines on non-clinical studies, which are applicable to multiple groups
Externí odkaz:
https://doaj.org/article/8620eeb94e914a818f74f665e298eeb7
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 12, Iss 4, Pp 395-403 (2022)
Pharmacokinetic (PK) studies of radiopharmaceuticals (RPs) are distinctive because of small concentrations of active ingredients. Whereas methods applicable to non-RP medicinal products cannot be used for RPs, radionuclide methods can provide an insi
Externí odkaz:
https://doaj.org/article/d12ca33186fb4118b4abfa9fdbcc84e5
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 11, Iss 4, Pp 255-262 (2021)
Radiopharmaceuticals differ from other medicines mainly by the specific nature of their pharmacological action based on radioactivity, by absence of multiple-dose regimens, and by miniscule concentrations of the active pharmaceutical ingredient (10-9
Externí odkaz:
https://doaj.org/article/bd384f0acf7d427b82b15aaa14139b1a
Autor:
O. E. Klementyeva, A. B. Bruskin, K. A. Lunyova, V. B. Bubenshchikov, K. E. Ternovskaya, A. S. Lunev, G. E. Kodina
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 9, Iss 4, Pp 66-71 (2020)
Introduction. Skin cancers came first in Russia in numbers of oncological diseases. Melanoma, making up only a small part of these cases, leads to the most serious consequences. The nuclear medicine methods application is necessary at the stages of c
Externí odkaz:
https://doaj.org/article/5f1fdf0ea27146ad9e7fc4618bff78b5
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 9, Iss 3, Pp 166-171 (2020)
Introduction. The early detection of tumor growth remains one of the most important tasks of diagnostic nuclear medicine. The vascular growth being created malignant neoplasms is a good target for the purpose. The molecular participants in the proces
Externí odkaz:
https://doaj.org/article/c7a209bd797d409cb0e5ffc68c0d14b5
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 130-134 (2019)
Rabbits' model of local radiation burn has been imaged clearly in 48 h past injection of 111In-labeled mesenchimal stem cells using three methods of injection (intravenously, locally, intracardially). SPECT Imaging of rabbits with model of skin radia
Externí odkaz:
https://doaj.org/article/3f4fce2b96d140ed9da1a62c8e59abc5
Autor:
V. E. Baulin, O. E. Klementyeva, Valery V. Ragulin, G. S. Tsebrikova, Iu. A. Mitrofanov, A. A. Larenkov, A. Ya. Maruk, A. S. Lunev, K. A. Luneva, A. Yu. Tsivadze, G. E. Kodina
Publikováno v:
Russian Journal of General Chemistry. 90:390-397
The binding of 68Ga to two organic ligands containing aminodiphosphonic groups (1,7-diamino-4-oxaheptane-1,1,7,7-tetraphosphonic and 1,7-diamino-4-hydroxycarbonylheptane-1,1,7,7-tetraphosphonic acids) has been examined. The stability and osteotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3c23f9b23f3d95a8aa2bb8e3c4576ae
https://doi.org/10.1134/s107036322003010x
https://doi.org/10.1134/s107036322003010x
Autor:
G. E. Kodina, Vladimir E. Baulin, Vitaly P. Solov'ev, Alexandr S. Lunev, G. S. Tsebrikova, Valery V. Ragulin, Iurii A. Mitrofanov, Aslan Yu. Tsivadse, Alesya Ya. Maruk, O. E. Klementyeva, Kristina A. Lunyova
Publikováno v:
Molecules
Volume 26
Issue 8
Molecules, Vol 26, Iss 2357, p 2357 (2021)
Volume 26
Issue 8
Molecules, Vol 26, Iss 2357, p 2357 (2021)
Two new aminodiphosphonic acids derived from salicylic acid and its phosphonic analogue were prepared through a simple and efficient synthesis. 2-[(2-Amino-2,2-diphosphono)ethyloxy]-benzoic acid 8 and 2-[(2-amino-2,2-diphosphono)ethyloxy]-5-ethyl-phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f2363a359183d12b99575f7b97f0ef
Autor:
Alesya Ya. Maruk, Aleksei E. Machulkin, O. E. Klementyeva, Kristina A. Lunyova, Marat Rakhimov, A. A. Larenkov
Publikováno v:
Molecules, Vol 25, Iss 2712, p 2712 (2020)
Molecules
Volume 25
Issue 11
Molecules
Volume 25
Issue 11
The folate receptor (FR) is a promising cell membrane-associated target for molecular imaging and radionuclide therapy of cancer (FR-&alpha
) and potentially also inflammatory diseases (FR-&beta
) through use of folic acid-based radioconjug
) and potentially also inflammatory diseases (FR-&beta
) through use of folic acid-based radioconjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52f040cb34dbe8ec6c0894611b2795
https://www.mdpi.com/1420-3049/25/11/2712
https://www.mdpi.com/1420-3049/25/11/2712
Autor:
M. V. Zhukova, O. E. Klementyeva, N. P. Lysenko, K. E. Ternovskaya, K. A. Petrosova, A. S. Lunev
Publikováno v:
Toxicological Review. :21-30
Toxicity effects of «Cigalin» and «Ferocit» lyophilizates used for formulation of the radiopharmaceutical preparation 68Ga-citrate were studied in animal organisms (rats, mice). Good tolerability, absence of pronounced intoxication symptoms, alle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc820882d4c20ee918a33a7d9686595
https://doi.org/10.36946/0869-7922-2016-1-21-30
https://doi.org/10.36946/0869-7922-2016-1-21-30