Zobrazeno 1 - 10
of 54
pro vyhledávání: '"O. E. Gichkun"'
Autor:
O. R. Bystrova, E. A. Stakhanova, M. I. Ilchuk, A. A. Ulybysheva, O. E. Gichkun, D. A. Saydulaev, O. P. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 24, Iss 3, Pp 94-101 (2022)
Fibrosis is one of the causes of kidney allograft loss, especially late after transplantation (up to 65% incidence after 2 years). The purpose of this literature review is to analyze studies examining noninvasive monitoring techniques for renal graft
Externí odkaz:
https://doaj.org/article/107cb93a720c4280958ab7bd2c819734
Autor:
O. P. Shevchenko, D. A. Velikiy, S. O. Sharapchenko, O. E. Gichkun, A. V. Marchenko, A. A. Ulybysheva, V. S. Pavlov, N. P. Моzheikо, N. N. Кoloskovа, A. O. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 23, Iss 3, Pp 73-81 (2021)
Myocardial fibrosis plays a key role in the pathogenesis of heart failure. A family of small non-coding signaling molecules, microRNAs (miRNAs), has been identified as promising profibrogenic biomarkers capable of signaling a possible risk of adverse
Externí odkaz:
https://doaj.org/article/1514bf0e110f4395b32d6d6dbcd2c0a2
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 23, Iss 3, Pp 180-185 (2021)
Transforming growth factor beta 1 (TGF-β1) is an immunosuppressive and profibrogenic cytokine capable of influencing the development of graft rejection and graft fibrosis in solid organ recipients. The TGF-β gene has a significant polymorphism that
Externí odkaz:
https://doaj.org/article/b40fe8aa52ad42809227146c9ec57835
Autor:
R. M. Kurabekova, O. M. Tsirulnikova, O. E. Gichkun, G. A. Olefirenko, I. E. Pashkova, A. A. Belchenkov, O. P. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 23, Iss 2, Pp 13-20 (2021)
Introduction. To prevent post-transplant complications associated with unbalanced immunosuppression, objective indicators reflecting the state of the immune system and associated with the immunosuppressant dose are required. In pediatric liver transp
Externí odkaz:
https://doaj.org/article/997f16983d9d4093922b5f7dfab84660
Autor:
D. A. Velikiy, O. E. Gichkun, S. O. Sharapchenko, N. P. Mozheiko, R. M. Kurabekova, O. P. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 4, Pp 20-26 (2021)
Objective: to determine the diagnostic value of miRNA-101 and miRNA-27 expression levels for acute hearttransplant rejection. Materials and methods. The study enrolled 46 heart recipients, among whom were 36 men (78.3%); the average age of recipients
Externí odkaz:
https://doaj.org/article/47bf077f80e7494b951f900e36deb396
Autor:
D. A. Velikiy, O. E. Gichkun, A. A. Ulybysheva, S. O. Sharapchenko, A. V. Marchenko, O. P. Shevchenko, A. O. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 3, Pp 69-78 (2020)
Objective: to analyze the correlation between the expression levels of microRNA-101, microRNA-142, microRNA-27, microRNA-339, and microRNA-424 and the plasma concentrations of biomarkers that are potentially significant for the diagnosis of post-tran
Externí odkaz:
https://doaj.org/article/6d7e4423265349bea2a56884a7fa09f1
Autor:
O. P. Shevchenko, S. O. Sharapchenko, O. M. Tsirulnikova, I. V. Pashkov, O. E. Gichkun, D. A. Velikiy, E. F. Shigaev, D. O. Oleshkevich, M. T. Bekov
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 2, Pp 86-96 (2020)
Objective: to evaluate the expression levels of miRNA (miR-27, miR-101, miR-142, miR-339 and miR-424) and its relationship with clinical and laboratory parameters in lung transplant recipients. Materials and methods. The study included 57 lung recipi
Externí odkaz:
https://doaj.org/article/8dfcacc3dcd3490aaee917b05232e17d
Autor:
O. E. Gichkun
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 2, Pp 165-170 (2020)
Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxic
Externí odkaz:
https://doaj.org/article/adb02a0099b942409397323050aa6cda
Autor:
O. P. Shevchenko, A. A. Ulybysheva, N. P. Mozheiko, O. E. Gichkun, E. A. Stakhanova, V. P. Vasilieva, A. O. Shevchenko
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 1, Pp 8-15 (2020)
Objective: to determine the diagnostic value of galectin-3 in transplant recipients with myocardial fibrosis and acute heart transplant rejection, verified by endomyocardial biopsy. Materials and methods. The study included 124 patients with end-stag
Externí odkaz:
https://doaj.org/article/1c9c8dca79884c6bba857f9d6aa30909
Publikováno v:
Vestnik Transplantologii i Iskusstvennyh Organov, Vol 22, Iss 1, Pp 26-34 (2020)
Objective: to conduct comparative analysis of the expression levels of microRNA-101, microRNA-142, microRNA- 27, microRNA-339 and microRNA-424 in patients with severe chronic heart failure and in heart recipients in the early and long-term period fol
Externí odkaz:
https://doaj.org/article/530c3bbe0b684df3bfc0e9a7cb731fed