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Akademický článek

Accurate measurements of dynamics and reproducibility in small genetic networks

Autor: Julien O Dubuis, Reba Samanta, Thomas Gregor

Publikováno v: Molecular Systems Biology, Vol 9, Iss 1, Pp 1-15 (2013)

Abstract Quantification of gene expression has become a central tool for understanding genetic networks. In many systems, the only viable way to measure protein levels is by immunofluorescence, which is notorious for its limited accuracy. Using the e

Externí odkaz: https://doaj.org/article/ba90900d6b58440bbbc14499aa68bd05

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Distribution of pathogens and antimicrobial resistance in bacteremia according to hospitalization duration: A nationwide surveillance study in Switzerland

Publikováno v: Buetti, Niccolò; Marschall, Jonas; Timsit, Jean-François; Atkinson, Andrew; Kronenberg, Andreas; Sommerstein, Rami (2021). Distribution of pathogens and antimicrobial resistance in bacteremia according to hospitalization duration: A nationwide surveillance study in Switzerland. Clinical microbiology and infection, 27(12), pp. 1820-1825. Elsevier 10.1016/j.cmi.2021.04.025
Clinical Microbiology and Infection, Vol. 27, No 12 (2021) pp. 1820-1825

OBJECTIVES Changing microorganism distributions and decreasing antibiotic susceptibility with increasing length of hospital stay have been demonstrated for the colonization or infection of selected organ systems. We wanted to describe microorganism d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12e1c2ba1c5006df64f8d933f94e13a
https://boris.unibe.ch/156267/1/1-s2.0-S1198743X21002123-main.pdf

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Akademický článek

The syncytial Drosophila embryo as a mechanically excitable medium.

Autor: Timon Idema, Julien O Dubuis, Louis Kang, M Lisa Manning, Philip C Nelson, Tom C Lubensky, Andrea J Liu

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77216 (2013)

Mitosis in the early syncytial Drosophila embryo is highly correlated in space and time, as manifested in mitotic wavefronts that propagate across the embryo. In this paper we investigate the idea that the embryo can be considered a mechanically-exci

Externí odkaz: https://doaj.org/article/ef14ef1ccfaf4312b2e53d0468b77cc5

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Characterizing non-linear effects of hospitalisation duration on antimicrobial resistance in respiratory isolates: an analysis of a prospective nationwide surveillance system

Publikováno v: Clinical Microbiology and Infection. 24:45-52

Objectives Our objective was to systematically study the influence of length of hospital stay on bacterial resistance in relevant respiratory tract isolates. Methods Using prospective epidemiological data from the National Swiss Antibiotic Resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec261ddc68e69cd4f17ccb9cae33a444
https://doi.org/10.1016/j.cmi.2017.05.018

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Accuracy of Sensititre YeastOne echinocandins epidemiological cut-off values for identification of FKS mutant Candida albicans and Candida glabrata: a ten year national survey of the Fungal Infection Network of Switzerland (FUNGINOS)

Autor: A. Kritikos, D. Neofytos, N. Khanna, P.W. Schreiber, K. Boggian, J. Bille, J. Schrenzel, K. Mühlethaler, R. Zbinden, T. Bruderer, D. Goldenberger, G. Pfyffer, A. Conen, C. Van Delden, S. Zimmerli, D. Sanglard, D. Bachmann, O. Marchetti, F. Lamoth, T. Bregenzer, U. Flückiger, C. Orasch, U. Heininger, M. Franciolli, L. Damonti, M. Rothen, C. Zellweger, P. Tarr, F. Fleisch, C. Chuard, V. Erard, S. Emonet, J. Garbino, C. van Delden, D. Genne, P. Bochud, T. Calandra, J. Chave, P. Graber, R. Monotti, O. Regionale, E. Bernasconi, O. Civico, M. Rossi, M. Krause, R. Piso, F. Bally, N. Troillet, G. Eich, J. Gubler, J. Fehr, A. Imhof, C. Ruef, C. Berger, H. Fankhauser, I. Heinzer, R. Frei, R. Hertel, M. Dolina, O. Petrini, O. Dubuis, S. Graf, M. Risch, E. Ritzler, D. Fracheboud, P. Rohner, R. Lienhardt, C. Andreutti-Zaugg, A. Gallusser, K. Herzog, U. Schibli, L. Tissière, D. Schultze

Publikováno v: Clinical Microbiology and Infection, Vol. 24, No 11 (2018) pp. 1214.e1-1214.e4

Objectives Echinocandins represent the first-line treatment of candidaemia. Acquired echinocandin resistance is mainly observed among Candida albicans and Candida glabrata and is associated with FKS hotspot mutations. The commercial Sensititre YeastO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4942d04f5df4bfd6d5fffcdc9cc412ae
https://www.zora.uzh.ch/id/eprint/153272/

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Positional Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical Framework

Autor: Julien O. Dubuis, Mariela D. Petkova, Thomas Gregor, Gašper Tkačik

Publikováno v: Genetics. 199:39-59

The concept of positional information is central to our understanding of how cells determine their location in a multicellular structure and thereby their developmental fates. Nevertheless, positional information has neither been defined mathematical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bf3eb6d93e4747220c989c7dbd3d12
https://doi.org/10.1534/genetics.114.171850

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Positional information, in bits

Autor: Julien O. Dubuis, Gašper Tkačik, William Bialek, Thomas Gregor, Eric Wieschaus

Publikováno v: Proceedings of the National Academy of Sciences. 110:16301-16308

Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be correlated with position, and these expression levels thus form a code

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d3be674ad1fc9e01ea62b1a34d098f
https://doi.org/10.1073/pnas.1315642110

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