Zobrazeno 1 - 10
of 178
pro vyhledávání: '"O. Csuka"'
Autor:
M Bak, J. Pozsár, Zsolt Tulassay, Barna Wichmann, G. Ivády, Ákos Pap, M Burai, N Le, J. Fillinger, Béla Molnár, R Szmola, Zsófia Brigitta Nagy, Á Tarpay, S Szanyi, O. Csuka
Publikováno v:
Pancreatology. 19:873-879
Background/Objectives Malignant pancreatobiliary strictures are in many cases clinically indistinguishable and present a major problem to endoscopy specialists. Intraductal sampling procedures such as brush cytology are commonly used for diagnosis wi
Publikováno v:
Clinical and Experimental Metastasis. 18:639-649
The organ-specific metastasis characterizes several human cancers, including colon carcinoma, a disease that frequently involves metastases in the liver. The data on the molecular mechanisms of liver metastasis would therefore be highly useful for pr
Autor:
Zs. Vadász, I. Mezo, Tibor Vántus, M. Idei, Aniko Horvath, Á. Balogh, O. Csuka, K. Pal, Gy. Kéri, I. Teplan, Judit Horvath, Marianna Mák
Publikováno v:
Biochemical and Biophysical Research Communications. 191:681-687
A series of new somatostatin analogs have been developed and tested for antitumor activity. Some analogs strongly inhibited tyrosine kinase activity of human colon tumor cells and this activity correlated well with their antiproliferative effect, but
Autor:
Anikó Horváth, Robert Ian Nicholson, Zs. Vadász, Judit Horvath, Agnes Balogh, Tamas Bajor, Gy. Kéri, Istvan Teplan, Tibor Vántus, O. Csuka, Gy. Bökönyi, I. Mezö
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 43:105-110
A series of novel gonadotropin releasing hormone (GnRH) and Somatostatin analogs have been developed in our laboratory and were screened for antiproliferative and signal transduction inhibitory effect. Our GnRH analog Folligen, had significant antitu
Autor:
G. Peley, Attila Bezzegh, B. Schumann, O. Csuka, I Besznyák, I Péter, J Tóth, I. Szamel, Szabolcs Ottó, Z. Doleschall
Publikováno v:
Europe PubMed Central
In this prospective study the correlation of pathological with biological prognostic factors and serum tumor markers has been investigated in 574 patients with primary invasive breast cancer. The p53 protein and Bax level correlated positively with t
Publikováno v:
Anticancer research. 28(5A)
The somatostatin structural derivative, TT-232, has a special 5-residue ring structure (D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2) and very different characteristics from the known growth hormone (GH) active somatostatin analogs. This somatostatin structur
Publikováno v:
Anticancer research. 26(4B)
The tumor growth inhibitory efficacy of the somatostatin structural derivative TT-232 was studied using different routes of administration and treatment schedules in various human tumor models. TT-232, containing a five-residue ring structure, has a
Publikováno v:
Anticancer research. 25(1A)
TT-232 is a structural derivative of the natural signal inhibitory peptide somatostatin, with selective antiproliferative and anti-inflammatory properties. TT-232 activates SSTR receptors (primarily the SSTR-1), which leads to irreversible cell cycle
Publikováno v:
In vivo (Athens, Greece). 19(2)
The drug accumulation of a human multidrug resistance 1 (mdr1) gene-transfected mouse lymphoma cell line and a multidrug resistance protein (MRP)-expressing human breast cancer cell line MDA-MB-231 was compared in the presence of sixteen flavonoids a
Publikováno v:
Anticancer research. 23(5A)
A somatostatin structural derivative (TT-232) has been developed in our laboratory with strong antiproliferative effect but no GH- release inhibitory activity. TT-232 inhibited tyrosine kinase activity of tumor cells lines and this inhibition correla