Zobrazeno 1 - 10
of 32
pro vyhledávání: '"O. Chumasova"'
Autor:
T. Tyrinova, A. Morenkova, M. Tikhonova, O. Chumasova, N. Ilina, A. Fedorova, A. Sizikov, A. Ostanin, E. Chernykh
Publikováno v:
Annals of the Rheumatic Diseases. 81:419.2-419
BackgroundHuman peripheral blood monocytes represent heterogeneous population and can be divided into three major populations, classical (CD14++CD16−), intermediate (CD14++CD16+) and non-classical (CD14+CD16++) monocytes. All three monocyte populat
Autor:
A. Alshevskaya, J. Zhukova, J. Lopatnikova, O. Chumasova, N. Shkaruba, A. Sizikov, S. Sennikov
Publikováno v:
Annals of the Rheumatic Diseases. 81:1181.1-1181
BackgroundLonger duration of rheumatoid arthritis (RA) is associated not only with higher disease severity, but also with lower treatment efficacy including anticytokine therapy. One of key mechanisms implementing this is changing in expression of cy
Autor:
Daniil Shevyrev, O. Chumasova, Vladimir A. Kozlov, Veroniсa Koksharova, A. Sizikov, Valeriy Tereshchenko
Publikováno v:
Experimental and Therapeutic Medicine
Rheumatoid arthritis (RA) is a chronic disease of connective tissue caused by intolerance to self-antigens. Regulatory T cells (Tregs) are key players in maintaining autotolerance through a variety of suppressor mechanisms. RA is generally believed t
Autor:
N. Shkaruba, Alina Alshevskaya, Aleksander V. Karaulov, Irina Evsegneeva, Julia Zhukova, Julia A. Lopatnikova, Aleksey Sizikov, Sergey Sennikov, Victor Gladkikh, O. Chumasova
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 288 (2019)
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 288 (2019)
Introduction: Tumor necrosis factor (TNF&alpha
) is an important proinflammatory cytokine in rheumatoid arthritis (RA) immune processes. However, TNF&alpha
activity and functions may be regulated by soluble receptors, which act as decoys, a
) is an important proinflammatory cytokine in rheumatoid arthritis (RA) immune processes. However, TNF&alpha
activity and functions may be regulated by soluble receptors, which act as decoys, a
Autor:
L. P. Konenkova, Alexandr A. Ostanin, O. Chumasova, Yu. D. Kurochkina, Marina A. Tikhonova, A. Sulutian, O. Yu. Leplina, Elena R. Chernykh, A. Sizikov, T. V. Tyrinova
Publikováno v:
Bûlleten' Sibirskoj Mediciny, Vol 16, Iss 4, Pp 195-206 (2018)
Purpose of the study. Comparative study of the phenotypic and functional properties of dendritic cells (DC) in groups of patients with rheumatoid arthritis (RA) receiving disease-modifying drugs, or biological drugs and (or) pulse therapy with high d
Autor:
O. Yu. Leplina, Alexandr A. Ostanin, A. Sizikov, Marina A. Tikhonova, T. V. Tyrinova, O. Chumasova, Elena R. Chernykh, Yu. D. Kurochkina
Publikováno v:
Medicinskaâ Immunologiâ, Vol 19, Iss 3, Pp 255-266 (2017)
Dendritic cells (DCs) play an important role in pathogenesis of rheumatoid arthritis (RA) and are considered a novel target for immune therapy. Under inflammatory conditions, local dendritic cells of non-lymphoid organs are thought to be differentiat
Autor:
O. Chumasova, Julia Zhukova, N. Shkaruba, Julia A. Lopatnikova, A. Sizikov, Sergey Sennikov, Alina Alshevskaya
Publikováno v:
SATURDAY, 15 JUNE 2019.
Background: TNF-alpha act as main proinflamantory cytokine in rheumatoid arthritis (RA) immune processes. However, TNF-alpha activity and functions may be regulate not only by soluble receptors (which act as decoys) but also by number, density, and c
Autor:
Julia A. Lopatnikova, Alina Alshevskaya, A. Sizikov, Julia Zhukova, Sergey Sennikov, O. Chumasova, N. Shkaruba
Publikováno v:
Annals of the Rheumatic Diseases. 80:482.2-483
Background:The balance of TNFα receptors expression on cells which are actively involved in immunopathological processes affects both the density of distribution of receptors on cells and co-expression in subsets. Previously it was shown that basic
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Autor:
Aleksey Sizikov, N. Shkaruba, Vasily V. Kurilin, Svetlana Falaleeva, I. A. Obleukhova, Sergey V. Sennikov, O. Chumasova
Publikováno v:
Human Immunology. 77:930-936
Background Since dendritic cells (DC) are involved in the development of autoimmune inflammation, researchers consider DC both as target cells for specific therapy of rheumatoid arthritis (RA) and as candidate cells for the development of cell-based