Zobrazeno 1 - 10 of 62 pro vyhledávání: '"O. Bruhn"'
2
Cloning of Two Thyrotropin-Releasing Hormone Receptor Subtypes from a Lower Vertebrate (Catostomus commersoni): Functional Expression, Gene Structure, and Evolution
Autor: Thomas O. Bruhn, Friedrich Buck, Oliver Dammann, Karl Lederis, Sönke Harder, Henk Zwiers, Dietmar Richter
Publikováno v: General and Comparative Endocrinology. 124:236-245
A PCR approach was used to clone thyrotropin-releasing hormone receptors (TRH-R) from the brain and anterior pituitary of the teleost Catostomus commersoni (cc), the white sucker. Two distinct TRH-R, designated ccTRH-R1 and ccTRH-R2, were identified.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364ddf862d84ad131903b506e3455be3
https://doi.org/10.1006/gcen.2001.7709
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3
Regulator of G Protein Signaling 4 Suppresses Basal and Thyrotropin Releasing-Hormone (TRH)-Stimulated Signaling by Two Mouse TRH Receptors, TRH-R1and TRH-R21
Autor: Xinping Lu, Thomas O. Bruhn, Marvin C. Gershengorn, Wei Wang, Friedrich Buck, Sönke Harder
Publikováno v: Endocrinology. 142:1188-1194
We cloned the mouse TRH receptor type 2 (mTRH-R2) gene, which is 92% identical with rat TRH-R2 and 50% identical with mTRH-R1 at the amino acid level, and identified an intron within the coding sequence that is not present in the TRH-R1 gene structur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f22c0e40f7bd207c4a4a971129970a1
https://doi.org/10.1210/endo.142.3.8019
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4
Juxtamembrane Regions in the Third Intracellular Loop of the Thyrotropin-Releasing Hormone Receptor Type 1 Are Important for Coupling to Gq*
Autor: Claude Brathwaite, Marvin C. Gershengorn, Wei Wang, Friedrich Buck, Thomas O. Bruhn, Sönke Harder
Publikováno v: Endocrinology. 141:3717-3722
Juxtamembrane residues in the putative third intracellular (I3) loops of a number of G protein-coupled receptors (GPCRs) have been shown to be important for coupling to G proteins. According to standard hydropathy analysis, the I3 loop of the mouse T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f8ff36a7b8b8d68649e6fe6e44c880
https://doi.org/10.1210/endo.141.10.7716
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5
Evidence for diverse pathways of hypophysiotropic hormone transport in mammals
Autor: Edythe L. P. Anthony, Alvar W. Gustafson, Thomas O. Bruhn, Patricia A. Overdeep
Publikováno v: Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 119:365-374
Comparative studies of mammalian hypothalamic-pituitary relationships have revealed striking variations in hypophysiotropic systems and in portal vascular architecture. Immunocytochemical studies indicate that mammalian GnRH, GHRH and somatostatin sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87bb27011615fd51f4ed07d4b1756f0
https://doi.org/10.1016/s0742-8413(98)00024-3
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7
Activation of thyrotropin-releasing hormone gene expression in cultured fetal diencephalic neurons by differentiating agents
Autor: T. G. Bolduc, Ivor M. D. Jackson, T. O. Bruhn, J. M. M. Rondeel, Lu-Guang Luo
Publikováno v: Endocrinology. 137:572-579
The present studies were undertaken to investigate the effect of 5-bromo-2'-deoxyuridine (BrdU; 50 microM) or forskolin/3-isobutyl-1-methylxanthine (F/I; 10/500 microM) on TRH gene expression in cultured fetal diencephalic cells. BrdU as well as drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eebfdd8d3a8dfd0dccad46a64a4fb34
https://doi.org/10.1210/endo.137.2.8593804
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8
Thyrotropin-Releasing Hormone Gene Expression in Cultured Anterior Pituitary Cells: Role of Gender
Autor: Jan M.M. Rondeel, T. G. Bolduc, Ivor M. D. Jackson, Thomas O. Bruhn
Publikováno v: Neuroendocrinology. 61:77-84
The present studies were undertaken to investigate the effect of gender on thyrotropin-releasing hormone (TRH) gene expression in cultured anterior pituitary (AP) cells. AP cells derived from 15-day-old male, female, or female pups that had been neon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddafe1edb9c6308bf6dca61383f21619
https://doi.org/10.1159/000126815
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9
Thyrotropin-releasing hormone (TRH) gene expression in the anterior pituitary. I. Presence of pro-TRH messenger ribonucleic acid and pro-TRH-derived peptide in a subpopulation of somatotrophs
Autor: Ivor M. D. Jackson, Jan M.M. Rondeel, T. G. Bolduc, Thomas O. Bruhn
Publikováno v: Endocrinology. 134:815-820
We have previously reported the presence of authentic pro-TRH-derived peptides in cultured anterior pituitary (AP) cells. The present studies were undertaken to determine whether pro-TRH mRNA could be demonstrated in the AP and to elucidate the cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3785f84f35247ae615b2e316e7f56d
https://doi.org/10.1210/endo.134.2.8299576
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10
Postsomatostatin Hypersecretion of Growth Hormone from Perifused Rat Anterior Pituitary Cells Is Dependent on Calcium Influx
Autor: Ivor M. D. Jackson, Matthew B. McFarlane, Thomas O. Bruhn
Publikováno v: Neuroendocrinology. 57:496-502
The role of ionic calcium (Ca2+) in the rebound secretion of growth hormone (GH) following termination of somatostatin (SRIF) administration was investigated in vitro by perifusion of acutely dispersed rat anterior pituitary cells. Treatment with 10
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cf75ba16fc24101d926d46cdd89087
https://doi.org/10.1159/000126397
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