Zobrazeno 1 - 10
of 80
pro vyhledávání: '"O. Brossa"'
Publikováno v:
Biochemical Journal. 274:869-873
1. The effects of free radicals on the capacity of beta L-crystallin to act as a substrate for the enzyme transglutaminase were investigated. 2. beta L-Crystallin was exposed to defined radical species that were generated radiolytically, and transglu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb00cf1fc3735fc8f28fcff75785082
https://doi.org/10.1042/bj2740869
https://doi.org/10.1042/bj2740869
Publikováno v:
Free Radical Research Communications. 11:223-229
In order to test whether a mild oxidative stress could promote the transglutaminase damaging effect on eye lens proteins, total lens soluble proteins and purified beta L-crystallin have been exposed to H2O2 slowly produced by the glucose-glucose oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c667dc760e01fe300b8740b895c9614
https://doi.org/10.3109/10715769009088919
https://doi.org/10.3109/10715769009088919
Autor:
Paola Costelli, Giuseppe Barbiero, O. Brossa, Rosa Angela Canuto, Riccardo Autelli, Marina Maggiora, Francesco M. Baccino, Gabriella Bonelli, Giuliana Muzio
In the AH-130 hepatoma, a poorly differentiated tumor, maintained by weekly transplantations in rats, a low percentage of cells spontaneously underwent apoptosis, mainly during the transition from logarithmic- to stationary-growth phase. It was possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414b3e187142377b43c49b5100cf7b74
http://hdl.handle.net/2318/53175
http://hdl.handle.net/2318/53175
Publikováno v:
Cell Growth and Oncogenesis ISBN: 9783764357276
Hepatoma cells have a below-normal content of polyunsaturated fatty acids; this reduces lipid peroxidation and production of cytotoxic and cytostatic aldehydes within the cells. If the arachidonic acid content is brought to values close to those of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5195e79ccd3ecc5612847d146bdb6c
https://doi.org/10.1007/978-3-0348-8950-6_19
https://doi.org/10.1007/978-3-0348-8950-6_19
Autor:
O. Brossa, Ronald Lindahl, Anna Maria Bassi, Rosanna Federa, Marina Maggiora, Rosa Angela Canuto, Margherita Ferro, Giuliana Muzio
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461376927
Hepatoma cells are less susceptible to oxidative stress than normal hepatocytes: the decreased content of polyunsaturated fatty acids in such cells decreases their capability to undergo lipid peroxidation (Gravela et al., 1975; Canuto et al., 1991; C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60396607f6634eb1f83db83b4346f88f
https://doi.org/10.1007/978-1-4615-5871-2_14
https://doi.org/10.1007/978-1-4615-5871-2_14
Autor:
Vito Michele Fazio, Enrico Gravela, Giuseppina Barrera, O. Brossa, Paradisi L, Mario U. Dianzani, Maria Giulia Farace
Publikováno v:
Europe PubMed Central
4-hydroxynonenal (HNE) is one of the major breakdown products of cellular lipid peroxidation. Its effects on proliferation, ornithine decarboxylase (ODC) activity and DNA synthesis have been investigated in leukemic cell lines. The cells were incubat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d88a8c5e4363aaf5a84eebca07d9b8
http://hdl.handle.net/2318/37897
http://hdl.handle.net/2318/37897
Publikováno v:
Research communications in chemical pathology and pharmacology. 70(2)
Calvatic acid (p-carboxyphenylazoxycyanide) is an antibiotic containing an azoxycyano group that displays carcinostatic activity. In the present work it has been shown that in AH-130 hepatoma and K562 leukemia cells the antibiotic, at low concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efb3040ebff984d44475e2d913d5b1f1
https://pubmed.ncbi.nlm.nih.gov/2277863
https://pubmed.ncbi.nlm.nih.gov/2277863
Publikováno v:
Free Radical Biology and Medicine. 9:83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e71e1b0c7e2350d00acd62f06b728d2
https://doi.org/10.1016/0891-5849(90)90464-t
https://doi.org/10.1016/0891-5849(90)90464-t
Publikováno v:
Cell Biology International Reports. 11:573-582
We have studied the activity, thiol-dependency and Km of ornithine decarboxylase (ODC) from the following sources: liver of rats subjected to partial hepatectomy or administered thioacetamide, the rat 3924A Morris hepatoma, the rat AH130 Yoshida asci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f5a813110b3ae77fe47f42f0d1bcb5
https://doi.org/10.1016/0309-1651(87)90137-8
https://doi.org/10.1016/0309-1651(87)90137-8