Zobrazeno 1 - 10
of 201
pro vyhledávání: '"O. Borgå"'
Publikováno v:
Veterinary and Comparative Oncology. 11:243-255
A new formulation of water-soluble paclitaxel (Paccal® Vet) has been developed for canine cancer patients, without the need for pre-medication (traditionally required in non-water-soluble paclitaxel formulations). The objective of the study was to d
Publikováno v:
Die Pharmazie. 64(7)
Grapefruit juice (GFJ) inhibits CYP3A activity in the gut wall, thereby decreasing first-pass metabolism of CYP3A substrates. In this study be evaluated the influence of GFJ on the systemic availability of budesonide, a CYP3A-metabolised drug, both f
Publikováno v:
European Journal of Cancer Supplements. 5:115-116
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 25(1)
The unbound fraction in serum, fu, is a critical parameter in describing and understanding the pharmacokinetics of NSAIDs. We compared fu for 6 different NSAIDs using ultrafiltration of pooled serum at pH 7.4 and 24C. Measurements covered a wide conc
Akademický článek
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Akademický článek
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Autor:
O. Borgå, Ingegerd Odar-Cederlöf
Publikováno v:
European Journal of Clinical Pharmacology. 7:31-37
Diphenylhydantoin (2 mg/kg) was infused intravenously in four uraemic patients and four healthy volunteers and its plasma concentration measured during and after the infusion. The plasma concentrations were considerably lower in the uraemic subjects
Publikováno v:
Clinical Chemistry. 22:246-249
Concentrations of diphenylhydantoin in 364 plasma samples have been measured both by radioimmunoassay and with a recently developed gas-chromatographic method, which requires only 0.1 ml of plasma per determination. There was an excellent correlation
Publikováno v:
British Journal of Clinical Pharmacology. 15:339-346
Cephapirin, a beta-lactam antibiotic, was administered intravenously to five healthy subjects in a dose of 1 g. Renal clearances of cephapirin, beta 2-microglobulin, uric acid and amino acids were measured during the experiment and compared to timed
Publikováno v:
European Journal of Clinical Pharmacology. 31:579-582
The pharmacokinetics of the glucocorticoid budesonide was studied in 6 children with asthma after i.v. injection of 0.5 mg and oral inhalation of 1 mg as an aerosol. Budesonide is a 1:1 mixture of the epimers 22 S and 22 R, which were assayed separat