Výsledky vyhledávání - "O. B. Filyukova"

Suppression of the Testis-Specific Transcription of the ZBTB32 and ZNF473 Genes in Germ Cell Tumors

Autor: S S, Bulanenkova, O B, Filyukova, E V, Snezhkov, S B, Akopov, L G, Nikolaev

Publikováno v: Acta naturae. 14(3)

The family of genes containing C2H2 zinc finger domains, which has more than 700 members, is one of the largest in the genome. Of particular interest are C2H2 genes with potential tissue-specific transcription, which determine the functional properti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bc46f45eb869ee1304d42b99ee7ce41
https://pubmed.ncbi.nlm.nih.gov/36348719

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A Universal Tumor-Specific Promoter for Cancer Gene Therapy

Autor: O. B. Filyukova, V. V. Pleshkan, E. V. Snezhkov, Eugene D. Sverdlov, A. V. Sass, I. V. Alekseenko

Publikováno v: Doklady Biochemistry and Biophysics. 480:158-161

An artificial double tandem tumor-specific promoter based on survivin and human telomerase reverse transcriptase gene promoters was constructed. Studies in in vitro and ex vivo therapeutic systems showed that the designed promoter exhibits a high act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeae8213bc08ea43e85ffbca26fdf67
https://doi.org/10.1134/s1607672918030092

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The Antitumor Efficacy of a Complex Based on Two-Vector System for Coexpression of the Suicide Gene Fcu1 and Cre Recombinase

Autor: Raisa I. Yakubovskaya, O. B. Filyukova, O. A. Bezborodova, I. V. Alekseenko, V. K. Potapov, Eugene D. Sverdlov, A. A. Pankratov, E. R. Nemtsova, M. B. Kostina

Publikováno v: Doklady Biochemistry and Biophysics. 483:326-328

In this study, we evaluated the antitumor activity of a gene therapy complex in which the tumor-specific control of the expression of the effector suicide gene FCU1 was performed using a two-vector system based on the site-specific Cre-LoxP recombina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd95142f75bb560dfe8077327378dd2
https://doi.org/10.1134/s1607672918060091

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Identification of some human genes oppositely regulated during esophageal squamous cell carcinoma formation and human embryonic esophagus development

Autor: Eugene D. Sverdlov, A. V. Sass, Gennady T. Sukhikh, M. B. Kostina, M. V. Zinovyeva, O. B. Filyukova, Tatyana V. Vinogradova, N. Y. Uspenskaya, Galina S. Monastyrskaya, E. P. Kopantzev

Publikováno v: Diseases of the Esophagus. 23:260-270

SUMMARY Here we directly compared gene expression profiles in human esophageal squamous cell carcinomas and in human fetal esophagus development. We used the suppression subtractive hybridization technique to subtract cDNAs prepared from tumor and no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560a369200766432529025173473cd1f
https://doi.org/10.1111/j.1442-2050.2009.01008.x

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Differences in gene expression levels between early and later stages of human lung development are opposite to those between normal lung tissue and non-small lung cell carcinoma

Autor: O. B. Filyukova, Alexander G. Tonevitsky, M. V. Zinovyeva, Marya B. Kostina, Tatyana V. Vinogradova, E.D. Sverdlov, E. P. Kopantzev, Gennady T. Sukhikh, Galina S. Monastyrskaya

Publikováno v: Lung Cancer. 62:23-34

We, for the first time, directly compared gene expression profiles in human non-small cell lung carcinomas (NSCLCs) and in human fetal lung development. Previously reported correlations of gene expression profiles between lung cancer and lung develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1429a1f7733c5a142bebde4e9d9e8205
https://doi.org/10.1016/j.lungcan.2008.02.011

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Genetic markers for lung and esophagus common precursor cells in human development

Autor: Galina S. Monastyrskaya, E. P. Kopantzev, O. B. Filyukova, M. B. Kostina, Eugene D. Sverdlov, A. V. Sass, M. V. Zinovyeva, Tatyana V. Vinogradova

Publikováno v: Doklady. Biochemistry and biophysics. 463

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb463bc559dc914ec62fcfb3bd0469b3
https://pubmed.ncbi.nlm.nih.gov/26335812

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The Transcription Activation of the RIG-I Gene Encoding the DEXH/D Protein in RH Cells Infected with Tick-Borne Encephalitis Virus

Autor: M. B. Kostina, S. N. Konovalova, Elena V. Protopopova, A. V. Kachko, Eugene D. Sverdlov, Lev G. Nikolaev, Galina S. Monastyrskaya, Valery B. Loktev, O. B. Filyukova

Publikováno v: Russian Journal of Bioorganic Chemistry. 30:129-133

It was demonstrated by subtractive hybridization that the infection of a human embryonic kidney cell line with tick-borne encephalitis virus causes an approximately tenfold transcription activation of the RIG-I gene, which encodes a protein of the DE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::344044fd3bfd578d638d74564490e176
https://doi.org/10.1023/b:rubi.0000023097.29436.0f

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[Untitled]

Autor: T. V. Velikodvorskaya, Valery B. Loktev, Galina S. Monastyrskaya, Eugene D. Sverdlov, Elena V. Protopopova, S. N. Konovalova, A. A. Kachko, O. B. Filyukova, Lev G. Nikolaev, B. G. Gavrilov

Publikováno v: Russian Journal of Bioorganic Chemistry. 29:154-159

The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6adff1bfca8f49791aa93b21ceff9fb0
https://doi.org/10.1023/a:1023260415910

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