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pro vyhledávání: '"O. Alexander H. Åstrand"'
Autor:
Marcel Sandberg, Eili Tranheim Kase, Ingebrigt Sylte, Pal Rongved, G. Hege Thoresen, Carl Henrik Görbitz, O. Alexander H. Åstrand
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:643-650
The generic, synthetic oxysterol 22(S)-hydroxycholesterol (22SHC) has shown antagonistic effects towards liver X receptor (LXR) in vitro and promising effects on plasma triacylglycerol level and body weight-gain in animal studies.1,2 On the contrary,
Autor:
Sidra Farzand Ali, Ragnhild E. Paulsen, Pal Rongved, Trond Vidar Hansen, Gulzeb Aziz, O. Alexander H. Åstrand
Publikováno v:
Bioorganicmedicinal chemistry. 21(17)
The lipophilic, cell-penetrating zinc chelator N,N,N',N',-tetrakis(2-pyridylmethyl) ethylenediamine (TPEN, 1) and the zinc chelating procaspase-activating compound PAC-1 (2) both have been reported to induce apoptosis in various cell types. The relat