Zobrazeno 1 - 10
of 114
pro vyhledávání: '"O. A. Pylaeva"'
Publikováno v:
Русский журнал детской неврологии, Vol 17, Iss 3, Pp 8-36 (2022)
Aim. To assess the efficacy and tolerability of lamotrigine (Sazar) for various forms of epilepsy, based on long-term experience of Svt. Luka's Association of Medical Institutions for the Diagnosis, Treatment, and Rehabilitation of Nervous System Dis
Externí odkaz:
https://doaj.org/article/7c51a22838c943ed9cd2ac0bb7e72d83
Publikováno v:
Русский журнал детской неврологии, Vol 17, Iss 1, Pp 6-95 (2022)
This article presents updated and revised diagnostic criteria for epilepsy syndromes proposed in 2021 by the Nosology and Definitions Taskforce of the International League Against Epilepsy (ILAE). The current classification of epilepsy syndromes was
Externí odkaz:
https://doaj.org/article/32f614723a224f4183d7ac8280c0aebf
Publikováno v:
Русский журнал детской неврологии, Vol 16, Iss 4, Pp 8-30 (2022)
Despite the significant advances in epileptology, including various new effective treatments for drug-resistant epilepsy in children, there is still a relatively large proportion of patients ineligible for surgery and alternative treatments (such as
Externí odkaz:
https://doaj.org/article/fefcb83a57a34cf6b30065e2f0181242
Autor:
G. V. Kuzmich, M. Yu. Bobylova, K. Yu. Mukhin, O. A. Pylaeva, L. Yu. Glukhova, A. S. Bagdasaryan, A. Yu. Zakharova
Publikováno v:
Русский журнал детской неврологии, Vol 16, Iss 1-2, Pp 42-57 (2021)
Angelman syndrome (AS) is a genetic disorder caused by a mutation in the maternal copy of the UBE3A gene and characterized by typical clinical manifestations (such as mental retardation, difficulty walking, and laughter) and specific changes on the e
Externí odkaz:
https://doaj.org/article/27b9cc1a55904a288015b636930d07e7
Publikováno v:
Русский журнал детской неврологии, Vol 16, Iss 1-2, Pp 10-41 (2021)
The disease caused by mutations in the CDKL5 gene (encoding cyclin-dependent kinase 5, CDK5) belongs to the group of early (infantile) epileptic encephalopathies caused by alterations in the genome. Currently, the disease is called “developmental e
Externí odkaz:
https://doaj.org/article/743aee6d9ca14825bedbb68a9a24867d
Autor:
O. A. Pylaeva
Publikováno v:
Русский журнал детской неврологии, Vol 15, Iss 3-4, Pp 41-54 (2021)
Hopantomide® is a drug containing calcium salt of hopantenic acid. The drug is registered and produced in Russia (Usolye-Siberian Chemical Pharmaceutical Factory) with the use of own raw materials and goes through a full production cycle, which guar
Externí odkaz:
https://doaj.org/article/607f1582b1394cb8acf1630b2307398c
Autor:
O. A. Pylaeva, K. Yu. Mukhin
Publikováno v:
Русский журнал детской неврологии, Vol 15, Iss 2, Pp 17-41 (2020)
Background. We have accumulated extensive experience in the use of lamotrigine in patients with epilepsy; its mechanism of action, effectiveness, safety, and tolerability are well known. The results of numerous studies indicate its high efficacy and
Externí odkaz:
https://doaj.org/article/f452ee36c008408b96dee51936c21043
Autor:
O. A. Pylaeva, K. Yu. Mukhin
Publikováno v:
Русский журнал детской неврологии, Vol 14, Iss 3, Pp 37-60 (2020)
Since epilepsy is a chronic disease of the nervous system that requires long-term therapy and regular intake of antiepileptic drugs, good tolerability of therapy is crucial for the quality of life of these patients. The main aim of antiepileptic trea
Externí odkaz:
https://doaj.org/article/d3f45fcca9024d41baa062da1395249e
Publikováno v:
Русский журнал детской неврологии, Vol 14, Iss 2, Pp 7-17 (2019)
Despite significant advances in epileptology, approximately one-third of patients suffer from drug-resistant epilepsy. Numerous approaches are currently available to treat epilepsy; however, there are still many patients with treatment-resistant epil
Externí odkaz:
https://doaj.org/article/fb4f5f89d7134dbea50d2afad8320f10
Publikováno v:
Русский журнал детской неврологии, Vol 13, Iss 4, Pp 7-22 (2019)
Women with epilepsy are at particular risk of developing side effects due to antiepileptic drugs (AED). Neuroendocrine disorders in women can be caused by both epilepsy itself and the therapy. This literature review aims to evaluate safety and tolera
Externí odkaz:
https://doaj.org/article/98048ededb2e4ea29c2de54be0ea1f84