The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly

Autor: Pablo Lara-Gonzalez, Christian O. De Groot, Andrew K. Shiau, Arshad Desai, Jack Houston, Joost Monen, Adina Gerson-Gurwitz, Karen Oegema, Bethany Davis

Publikováno v: Molecular Biology of the Cell. 32:1193-1201

Caenorhabditis elegans builds centromeres using the histone H3 variant CENP-A but lacks a CENP-A-specific chaperone. This article shows that the extended N-terminal tail of C. elegans CENP-A, which interacts with the conserved loading factor KNL-2 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d92fa5f26e311c5361f3c09c5c80572d
https://doi.org/10.1091/mbc.e20-12-0798

COLREGs-aware Trajectory Optimization for Autonomous Surface Vessels

Autor: A. Tsolakis, D. Benders, O. de Groot, R.R. Negenborn, V. Reppa, L. Ferranti

Publikováno v: IFAC-PapersOnLine, 55(31)

This paper presents a rule-compliant trajectory optimization method for the guidance and control of autonomous surface vessels. The method builds on Model Predictive Contouring Control and incorporates the International Regulations for Preventing Col

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f121892c7917aab0840ecfd913393aa3
https://doi.org/10.1016/j.ifacol.2022.10.441

Fatal hyperammonaemia due to late-onset ornithine transcarbamylase deficiency

Autor: G P, Bijvoet, C J M, van der Sijs-Bos, J P M, Wielders, O A, Groot

Publikováno v: The Netherlands journal of medicine. 74(1)

In this case report we describe a 67-year-old male, admitted to the ICU with pneumonia who unexpectedly developed a fatal coma due to hyperammonaemia. At postmortem the diagnosis late-onset ornithine transcarbamylase deficiency was made. The non-spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3d15bf784fe6d4da6fc5ac20c423ea5
https://pubmed.ncbi.nlm.nih.gov/26819360

Molecular Insights into Mammalian End-binding Protein Heterodimerization

Autor: Michel O. Steinmetz, Fred F. Damberger, Christian O. De Groot, Guido Capitani, Martin A. Schärer, Ilia Grigoriev, Ilian Jelesarov, Rubén M. Buey, Kurt Wüthrich, Saša Bjelić, Anna Akhmanova, Neel Sarovar Bhavesh

Publikováno v: Journal of Biological Chemistry, 285(8), 5802-5814. American Society for Biochemistry and Molecular Biology Inc.
The Journal of biological chemistry

Microtubule plus-end tracking proteins (+TIPs) are involved in many microtubule-based processes. End binding (EB) proteins constitute a highly conserved family of +TIPs. They play a pivotal role in regulating microtubule dynamics and in the recruitme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bbf21dd4ca65e85d9ed118ef5252b5
https://doi.org/10.1074/jbc.m109.068130

Should medical students learn to develop a personal formulary?

Autor: H. V. Hogerzeil, Milan C. Richir, P. D. Bezemer, C. Van Kan, O. A. Groot, Milan Kriška, L. E. Ziganshina, L. Van Bortel, Nageeb Hassan, Emilio J. Sanz, H. A. Bakathir, Karen I. Barnes, C. W. Mulder, M. Thomas, L. Wewerinke, T.P.G.M. de Vries, B. Santoso, Johannes M.A. Daniels

Publikováno v: European Journal of Clinical Pharmacology

Objective This study was performed to determine whether students who are trained in developing a personal formulary become more competent in rational prescribing than students who have only learned to use existing formularies. Methods This was a mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853945d68b394c5e31fa88cf957db6b0
https://doi.org/10.1007/s00228-008-0465-y