Zobrazeno 1 - 10
of 41
pro vyhledávání: '"O. A. Gansow"'
Autor:
F. P. Auteri, Paul C. Lauterbur, D. S. Schneider, M. W. Brechbiel, O. A. Gansow, R. L. Belford, Robert B. Clarkson, J. W. Chen, Erik C. Wiener
Publikováno v:
Journal of the American Chemical Society. 118:7774-7782
We studied the molecular dynamics of vanadyl−chelate complexes covalently attached to the surface of cascade polymers, dendrimers. The rotational correlation times of the ion−chelate complex were determined from computer simulations of their EPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe59805a8527dfcc7fc7b76e0c5048cc
https://doi.org/10.1021/ja9536126
https://doi.org/10.1021/ja9536126
Autor:
J A, Carrasquillo, J D, White, C H, Paik, A, Raubitschek, N, Le, M, Rotman, M W, Brechbiel, O A, Gansow, L E, Top, P, Perentesis, J C, Reynolds, D L, Nelson, T A, Waldmann
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(2)
Monoclonal antibodies (MoAb) labeled with 90Y are being used for radioimmunotherapy. Because 90Y is a beta emitter, quantitative information from imaging is suboptimal. With the concept of a "matched pair" of isotopes, 111In is used as a surrogate ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::347b6eb2062f905649836ef10877548c
https://pubmed.ncbi.nlm.nih.gov/10025834
https://pubmed.ncbi.nlm.nih.gov/10025834
Autor:
T K, Nikula, M R, McDevitt, R D, Finn, C, Wu, R W, Kozak, K, Garmestani, M W, Brechbiel, M J, Curcio, C G, Pippin, L, Tiffany-Jones, M W, Geerlings, C, Apostolidis, R, Molinet, O A, Gansow, D A, Scheinberg
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(1)
The alpha-particle-emitting radionuclides have several physical characteristics that make them attractive candidates for radioimmunotherapy: (a) high linear energy transfer; (b) short path lengths (50-80 microm); and (c) limited ability of cells to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a39d6ace035dc0448a7e18301ec6faa
https://pubmed.ncbi.nlm.nih.gov/9935073
https://pubmed.ncbi.nlm.nih.gov/9935073
Autor:
H, Kobayashi, C, Wu, T M, Yoo, B F, Sun, D, Drumm, I, Pastan, C H, Paik, O A, Gansow, J A, Carrasquillo, M W, Brechbiel
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(5)
We evaluated the in vivo stability and biodistribution of four isomers (CHX-A', CHA-A", CHX-B' and CHX-B") of 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaaceti c acid (CHX-DTPA), a recently developed backbone-substituted derivative o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33e7db60c9412167f24748c348fc9821
https://pubmed.ncbi.nlm.nih.gov/9591585
https://pubmed.ncbi.nlm.nih.gov/9591585
Autor:
E, Horak, F, Hartmann, K, Garmestani, C, Wu, M, Brechbiel, O A, Gansow, N F, Landolfi, T A, Waldmann
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(12)
The specificity, toxicity and efficacy of lead (212Pb) radioimmunotherapy were evaluated in nude mice bearing the SK-OV-3 human ovarian tumor cell line expressing the HER2/neu proto-oncogene.The therapeutic agent used was the tumor-specific anti-HER2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4222fc0ef0625b5ac95f0af1547e244
https://pubmed.ncbi.nlm.nih.gov/9430475
https://pubmed.ncbi.nlm.nih.gov/9430475
Autor:
Andrew M. Scott, R. D. Finn, Lloyd J. Old, S. M. Larson, T J Yao, E Riedel, Sydney Welt, C. Williams, Els C. Barendswaard, C. R. Divgi, Keren Coplan, O A Gansow
Publikováno v:
International Journal of Oncology.
Monoclonal antibody (mAb) A33 detects a glycoprotein homogeneously expressed by > 95% of human colon cancers and by normal colon cells. The A33 antigen is not secreted or shed and after mAb A33 binds to antigen on the cell membrane, a fraction of mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8f8bf9c0503c3779f5d35d775e3e31
https://doi.org/10.3892/ijo.12.1.45
https://doi.org/10.3892/ijo.12.1.45
Autor:
L, Lang, E, Jagoda, C, Wu, M W, Brechbiel, O A, Gansow, I, Pastan, C H, Paik, J A, Carrasquillo, W C, Eckelman
Publikováno v:
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR). 41(2)
Monoclonal antibodies (MoAbs) were proposed as candidates for selective tumor targeting based on their high binding affinity for tumors and the absence of binding by normal tissue. However, the exclusive and complete transport of the drug have been f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::435c1cc9b574ab13bee75807a216c6be
https://pubmed.ncbi.nlm.nih.gov/9203844
https://pubmed.ncbi.nlm.nih.gov/9203844
Autor:
T A, Waldmann, J D, White, J A, Carrasquillo, J C, Reynolds, C H, Paik, O A, Gansow, M W, Brechbiel, E S, Jaffe, T A, Fleisher, C K, Goldman, L E, Top, R, Bamford, E, Zaknoen, E, Roessler, C, Kasten-Sportes, R, England, H, Litou, J A, Johnson, T, Jackson-White, A, Manns, B, Hanchard, R P, Junghans, D L, Nelson
Publikováno v:
Blood. 86(11)
Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus human T-cell lymphotropic virus-I. It is an aggressive leukemia with a median survival time of 9 months; no chemotherapy regimen appears successful in inducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3af2053a1def80e815c59b25601c4f57
https://pubmed.ncbi.nlm.nih.gov/8652853
https://pubmed.ncbi.nlm.nih.gov/8652853
Autor:
J G, Jurcic, P C, Caron, T K, Nikula, E B, Papadopoulos, R D, Finn, O A, Gansow, W H, Miller, M W, Geerlings, R P, Warrell, S M, Larson
Publikováno v:
Cancer research. 55
M195, a mouse monoclonal antibody reactive with the early myeloid antigen CD33, has been shown to target leukemia cells in patients and to reduce large leukemic burdens when labeled with 131I. A complementarity-determining region-grafted, humanized v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eda92ffd21cf3b7ee884d5a3fbaea78d
https://pubmed.ncbi.nlm.nih.gov/7493368
https://pubmed.ncbi.nlm.nih.gov/7493368
Autor:
F, Hartmann, E M, Horak, K, Garmestani, C, Wu, M W, Brechbiel, R W, Kozak, J, Tso, S A, Kosteiny, O A, Gansow, D L, Nelson
Publikováno v:
Cancer research. 54(16)
The efficacy, specificity, and toxicity of bismuth (212Bi) alpha particle-mediated radioimmunotherapy was evaluated in nude mice bearing a murine lymphoma transfected with the human CD25 [human Tac; interleukin 2 receptor alpha (IL-2R alpha)] gene. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c203f885dc7b3e396684be20935f0d2d
https://pubmed.ncbi.nlm.nih.gov/8044783
https://pubmed.ncbi.nlm.nih.gov/8044783