Zobrazeno 1 - 10
of 24
pro vyhledávání: '"O. A. Fil'ko"'
Autor:
O. A. Fil'ko, Dolgo-Saburov Vb, L. G. Kubarskaya, S. G. Dagaev, R. I. Glukhova, L. A. Mukovskii, V. I. Sanotskii, A. V. Khrabrova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 137:468-470
We studied the functional role of individual subtypes of muscarinic cholinoceptors in the pathogenesis of neuroleptic parkinsonism in rats. Blockade of M4 receptors prevented the development of extrapyramidal disorders, which was abolished by simulta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258fd39960706cae4d57113867b64438
https://doi.org/10.1023/b:bebm.0000038155.56296.50
https://doi.org/10.1023/b:bebm.0000038155.56296.50
Autor:
Dolgo-Saburov Vb, S. G. Dagaev, N. E. Solov'eva, A. B. Kosmachev, V. I. Sanotskii, O. A. Fil'ko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 137:164-166
Correction of neuroleptic-induced parkinsonism in rats with two central cholinoblockers atropine and pentifine (acetylene aminoalcohol synthesized at Institute of Toxicology) were studied by measuring the content of acetylcholine in the striatum. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effb49b5587d1ab2380c542b5f5748e9
https://doi.org/10.1023/b:bebm.0000028130.09656.ac
https://doi.org/10.1023/b:bebm.0000028130.09656.ac
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3fab3b05652bdb964fcd52871b7635
https://doi.org/10.1002/chin.199843171
https://doi.org/10.1002/chin.199843171
Publikováno v:
Pharmaceutical Chemistry Journal. 32:301-303
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88435f10fe0f36c8f4a7330fe6a71ced
https://doi.org/10.1007/bf02580513
https://doi.org/10.1007/bf02580513
Autor:
Podosinovikova Np, A. V. Khrabrova, A. B. Kosmachev, N. M. Libman, S. G. Dagaev, V. I. Sanotskii, Beliaev Va, Dolgo-Saburov Vb, O. A. Fil'ko, L. G. Kubarskaya
Publikováno v:
Bulletin of experimental biology and medicine. 137(2)
We studied the relationship between the efficiency of muscarinic receptor antagonists in preventing haloperidol-induced catatonia and their activity in tests for the interaction of ligands with various subtypes of muscarinic receptors (M1-M4) in rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d87efea0fa3ecfd1b8581d09c62645
https://pubmed.ncbi.nlm.nih.gov/15273762
https://pubmed.ncbi.nlm.nih.gov/15273762
Autor:
S G, Dagaev, A B, Kosmachev, N M, Libman, L G, Kubarskaya, A V, Khrabrova, V I, Sanotskii, O A, Fil'ko, V B, Dolgo-Saburov
Publikováno v:
Bulletin of experimental biology and medicine. 135(5)
Quantitative assessment of selective blockade of M4-subtype muscarinic receptors was performed by the number of pilocarpine-induced movements of lower jaw in rats. Three antagonists (atropine, cyclodol, and glipin) were used in the experiments. Glipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd42e462101d33c7eb15ed8299f90162
https://pubmed.ncbi.nlm.nih.gov/12910282
https://pubmed.ncbi.nlm.nih.gov/12910282
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 65(1)
The experiments on rats showed different activities of pilocarpine, arecoline, and DDVF in tests for the onset of bradycardia and hypersalivation. A comparative study of the activity of selective M-cholinoblockers in preventing the arrhythmias induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37ce028657cd081da4c5341fc6ec8a36
https://pubmed.ncbi.nlm.nih.gov/12025782
https://pubmed.ncbi.nlm.nih.gov/12025782
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 64(3)
The results of in vitro experiments showed that the receptor selectivity of the M-cholinoblocker tropacin (in contrast to that of amedine) is pH-dependent. A difference observed in the characteristics of tropacin selectivity in vivo and in vitro is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5872127c68b103b01db7319bceb8e00
https://pubmed.ncbi.nlm.nih.gov/11558434
https://pubmed.ncbi.nlm.nih.gov/11558434
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 63(4)
In the experiments in vivo it is found that the receptor selectivity of muscarine antagonist glypine is time-dependent unlike atropine, amedine, benzhexol, benactyzine, and thropacin. Using modulation of the metabolic system activity it is shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5c6669ac10f959fbaf02ce7452cdee6
https://pubmed.ncbi.nlm.nih.gov/11022298
https://pubmed.ncbi.nlm.nih.gov/11022298
Autor:
A V, Khrabrova, A O, Zagrebin, A B, Kosmachev, L G, Kubarskaia, A V, Lychakov, N M, Libman, T N, Savateeva, T A, Titkova, V D, Tonkopiĭ, O A, Fil'ko, Z I, Khobotova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 63(2)
Experiments on rodents showed that pentifin, a muscarine antagonist belonging to the group of acetylene amines, possesses a pronounced antiparkinsonian activity. Pentifin is superior in the breadth of therapeutic action and tolerance characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34dcc92b58e23527057048e6d78c1d0a
https://pubmed.ncbi.nlm.nih.gov/10834089
https://pubmed.ncbi.nlm.nih.gov/10834089