Zobrazeno 1 - 10
of 4 533
pro vyhledávání: '"O-Glycosylation"'
Autor:
Xiaoxin Sun, Haotian Wu, Ling Tang, Abdullah Al-Danakh, Yuli Jian, Li Gong, Congchen Li, Xiao Yu, Guang Zeng, Qiwei Chen, Deyong Yang, Shujing Wang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Bladder cancer (BC) ranks as the sixth cancer in males and the ninth most common cancer worldwide. Conventional treatment modalities, including surgery, radiation, chemotherapy, and immunotherapy, have limited efficacy in certain advanced in
Externí odkaz:
https://doaj.org/article/8e80721f6d8f4519b6b13d3ce4046fcb
Autor:
Christine Rempfer, Sebastian N.W. Hoernstein, Nico van Gessel, Andreas W. Graf, Roxane P. Spiegelhalder, Anne Bertolini, Lennard L. Bohlender, Juliana Parsons, Eva L. Decker, Ralf Reski
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2580-2594 (2024)
Hydroxylation of prolines to 4-trans-hydroxyproline (Hyp) is mediated by prolyl-4 hydroxylases (P4Hs). In plants, Hyps occur in Hydroxyproline-rich glycoproteins (HRGPs), and are frequently O-glycosylated. While both modifications are important, e.g.
Externí odkaz:
https://doaj.org/article/498a1b01e65e490cb7f194d15b8df6ee
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Immune escape is one of the causes of poor prognosis in breast cancer (BC). Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first speed-limiting enzyme of the hexosamine biosynthesis pathway (HBP) and is essential for
Externí odkaz:
https://doaj.org/article/f0da6a1949734d68bacb8d18d64fae45
Autor:
Xu Zhijue, Zhang Han, Tian Jiaqi, Ku Xin, Wei Rumeng, Hou Jingli, Zhang Can, Yang Fang, Zou Xia, Li Yang, Kaji Hiroyuki, Tao Sheng-Ce, Kuno Atsushi, Yan Wei, Da Lin-Tai, Zhang Yan
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1118-1129 (2024)
Protein O-glycosylation, also known as mucin-type O-glycosylation, is one of the most abundant glycosylation in mammalian cells. It is initially catalyzed by a family of polypeptide GalNAc transferases (ppGalNAc-Ts). The trimeric spike protein (S) of
Externí odkaz:
https://doaj.org/article/634c917b7daf41bca9cda00eb9030346
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background B3GNT7, a glycosyltransferase of significant importance that is highly expressed in intestinal epithelial cells, plays a pivotal role in intestinal physiological processes. This study elucidates novel insights into the potential r
Externí odkaz:
https://doaj.org/article/c1a95bb534964254ac91f835703d209b
Publikováno v:
mLife, Vol 3, Iss 1, Pp 57-73 (2024)
Abstract O‐glycosylation is an ancient yet underappreciated protein posttranslational modification, on which many bacteria and viruses heavily rely to perform critical biological functions involved in numerous infectious diseases or even cancer. Bu
Externí odkaz:
https://doaj.org/article/a3a9b5976da141c7a4c74d36859a49ae
Akademický článek
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Autor:
Mei‐Chun Lin, Ya‐Ting Chuang, Hsin‐Yi Wu, Chia‐Lang Hsu, Neng‐Yu Lin, Min‐Chuan Huang, Pei‐Jen Lou
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 350-368 (2024)
Cells in the tumor microenvironment (TME) communicate via membrane‐bound and secreted proteins, which are mostly glycosylated. Altered glycomes of malignant tumors influence behaviors of stromal cells. In this study, we showed that the loss of core
Externí odkaz:
https://doaj.org/article/e9ed1e8e7af94aa582632080fc33d22f
Publikováno v:
Food Materials Research, Vol 4, Iss 1, Pp 1-6 (2024)
Edible bird's nest (EBN) is considered a delicacy in Chinese cuisine. The nests are produced by male swiftlets (Aerodramus sp.). Due to their high price, the nutritional benefit from EBN can currently only be afforded by affluent consumers. Therefore
Externí odkaz:
https://doaj.org/article/31b28ea3eaf84ee1bedb0c65c3766d57
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10433 (2024)
Xanthohumol (1) is a major prenylated flavonoid in hops (Humulus lupulus L.) which exhibits a broad spectrum of health-promoting and therapeutic activities, including anti-inflammatory, antioxidant, antimicrobial, and anticancer effects. However, due
Externí odkaz:
https://doaj.org/article/e1f2d046675544bdb367c2737cb8817d