Zobrazeno 1 - 10
of 45
pro vyhledávání: '"O Y Chan"'
Autor:
Quy Xiao Xuan Lin, Deepa Rajagopalan, Akshamal M. Gamage, Le Min Tan, Prasanna Nori Venkatesh, Wharton O. Y. Chan, Dilip Kumar, Ragini Agrawal, Yao Chen, Siew-Wai Fong, Amit Singh, Louisa J. Sun, Seow-Yen Tan, Louis Yi Ann Chai, Jyoti Somani, Bernett Lee, Laurent Renia, Lisa F P Ng, Kollengode Ramanathan, Lin-Fa Wang, Barnaby Young, David Lye, Amit Singhal, Shyam Prabhakar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Due to the paucity of longitudinal molecular studies of COVID-19, particularly those covering the early stages of infection (Days 1-8 symptom onset), our understanding of host response over the disease course is limited. We perform longitudi
Externí odkaz:
https://doaj.org/article/9f2600a9ca174e47b4b821252b56c6f1
Autor:
Vivian Chih-Wei Chen, Craig Ryan Joseph, Wharton O. Y. Chan, Wan Rong Sia, Qi Su, Xin Xiu Sam, Hemavathi Tamilarasan, Yun Yan Mah, Wei Lun Ng, Joe Yeong, Lin-Fa Wang, Thinesh L. Krishnamoorthy, Wei-Qiang Leow, Matae Ahn, Wan Cheng Chow
Publikováno v:
Viruses, Vol 16, Iss 10, p 1646 (2024)
Inflammasome is linked to many inflammatory diseases, including COVID-19 and autoimmune liver diseases. While severe COVID-19 was reported to exacerbate liver failure, we report a fatal acute-on-chronic liver failure (ACLF) in a stable primary biliar
Externí odkaz:
https://doaj.org/article/7d21d18c0b0e4d679d8734ac22353137
Autor:
Meisam Yousefi, Wai Suet Lee, Wharton O. Y. Chan, Wei He, Marcus G. Mah, Cythia Lingli Yong, Joshua M. Deerain, Lijin Wang, Camille Arcinas, Biaoguo Yan, Dewei Tan, Wan Rong Sia, Akshamal M. Gamage, Jinxuan Yang, Alan Chen-Yu Hsu, Shang Li, Martin Linster, Xinglou Yang, Sujoy Ghosh, Danielle E. Anderson, Gavin J. D. Smith, Chee Wah Tan, Lin-Fa Wang, Yaw Shin Ooi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
The emergence of novel betacoronaviruses has posed significant financial and human health burdens, necessitating the development of appropriate tools to combat future outbreaks. In this study, we have characterized a human cell line, IGROV-1, as a ro
Externí odkaz:
https://doaj.org/article/b47f4408b06d4266b90736a4ac87c4ae
Autor:
Akshamal M. Gamage, Kai Sen Tan, Wharton O. Y. Chan, Zhe Zhang Ryan Lew, Jing Liu, Chee Wah Tan, Deepa Rajagopalan, Quy Xiao Xuan Lin, Le Min Tan, Prasanna Nori Venkatesh, Yew Kwang Ong, Mark Thong, Raymond Tzer Pin Lin, Shyam Prabhakar, De Yun Wang, Lin-Fa Wang
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The dynamics of SARS-CoV-2 infection in COVID-19 patients are highly variable, with a subset of patients demonstrating prolonged virus shedding, which poses a significant challenge for disease management and transmission control. In this stu
Externí odkaz:
https://doaj.org/article/90f0bab02d34444a9ecc6db6b4004829
Autor:
Akshamal M Gamage, Kai Sen Tan, Wharton O Y Chan, Jing Liu, Chee Wah Tan, Yew Kwang Ong, Mark Thong, Anand K Andiappan, Danielle E Anderson, De Yun Wang, Lin-Fa Wang
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009130 (2020)
The novel coronavirus SARS-CoV-2 is the causative agent of Coronavirus Disease 2019 (COVID-19), a global healthcare and economic catastrophe. Understanding of the host immune response to SARS-CoV-2 is still in its infancy. A 382-nt deletion strain la
Externí odkaz:
https://doaj.org/article/22bd2e51569a4104a446fde97cbfe7b9
Publikováno v:
Nature Reviews. Immunology
Understanding antiviral immune responses in bats, which are reservoirs for many emerging viruses, could aid the response to future epidemics. Here, we discuss five key areas in which greater consensus among the bat research community is necessary to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f42f0912223d1ea969c279733487d98
http://europepmc.org/articles/PMC7919622
http://europepmc.org/articles/PMC7919622
Publikováno v:
Hong Kong medical journal = Xianggang yi xue za zhi. 21(1)
Objective To review the result of the implementation of treatment protocol for post-chemotherapy sepsis in haematological malignancy patients. Design Case series with internal comparison. Setting Accident and Emergency Department, Queen Elizabeth Hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2596416a4e1305e681eae24958090694
https://pubmed.ncbi.nlm.nih.gov/25306894
https://pubmed.ncbi.nlm.nih.gov/25306894
Publikováno v:
European Respiratory Journal. 10:2825-2828
Maximal static inspiratory and expiratory mouth pressures (PI,max and PE,max, respectively) enable the noninvasive measurement of global respiratory muscle strength. The aim of this study was primarily to obtain normal values of PI,max and PE,max for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743d139da0b1c54d9fdcc65396cb4f6f
https://doi.org/10.1183/09031936.97.10122825
https://doi.org/10.1183/09031936.97.10122825
Publikováno v:
Occupational Medicine. 43:143-148
Health complaints, blood pressure, sleep and sickness absence experience were studied in 308 female electronics workers employed for at least one year on 12 h shifts--253 on permanent and 55 on rotating schedules. Seventy-five 8 h day workers acted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4056cf897f961805c4e2890805b608
https://doi.org/10.1093/occmed/43.3.143
https://doi.org/10.1093/occmed/43.3.143
Publikováno v:
Occupational Medicine. 40:111-115
Sixty-one male spice grinders from 14 factories were studied to determine if they had any skin problems, respiratory symptoms or hearing loss associated with their work. All subjects were interviewed and examined. Audiometric examinations were arrang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5c87ec67d9ea0bf97471a255107d50
https://doi.org/10.1093/occmed/40.3.111
https://doi.org/10.1093/occmed/40.3.111