Zobrazeno 1 - 10
of 411
pro vyhledávání: '"O Watson"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Electrophysiological recordings from single neurons are crucial for understanding the complex functioning of the brain and for developing eventual therapeutic interventions. For electrophysiology, the accuracy and fidelity of invasive implantations o
Externí odkaz:
https://doaj.org/article/8c47fbed46cf47d3bb0e21f54ac54767
Autor:
Haley M. Scott, Mackenzie H. Smith, Aja K. Coleman, Kaitlyn S. Armijo, Morgan J. Chapman, Summer L. Apostalo, Allison R. Wagner, Robert O. Watson, Kristin L. Patrick
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113816- (2024)
Summary: Tight regulation of macrophage immune gene expression is required to fight infection without risking harmful inflammation. The contribution of RNA-binding proteins (RBPs) to shaping the macrophage response to pathogens remains poorly underst
Externí odkaz:
https://doaj.org/article/b8e107d3d69e4d6bae0a464021f10cb9
Autor:
Lezio S. Bueno-Junior, Carolyn E. Jones-Tinsley, Noah E. P. Milman, Peyton T. Wickham, Brendon O. Watson, Miranda M. Lim
Publikováno v:
Royal Society Open Science, Vol 10, Iss 7 (2023)
Early-life sleep disruption (ELSD) has been shown to have long-lasting effects on social behaviour in adult prairie voles (Microtus ochrogaster), including impaired expression of pair bonding during partner preference testing. However, due to the lim
Externí odkaz:
https://doaj.org/article/d79c40887a5240ca98e27a0cfc0604e6
Autor:
Huntly M Morrison, Julia Craft, Rafael Rivera-Lugo, Jeffery R Johnson, Guillaume R Golovkine, Samantha L Bell, Claire E Dodd, Erik Van Dis, Wandy L Beatty, Shally R Margolis, Teresa Repasy, Isaac Shaker, Angus Y Lee, Russell E Vance, Sarah A Stanley, Robert O Watson, Nevan J Krogan, Daniel A Portnoy, Bennett H Penn, Jeffery S Cox
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011088 (2023)
Macrophages employ an array of pattern recognition receptors to detect and eliminate intracellular pathogens that access the cytosol. The cytosolic carbohydrate sensors Galectin-3, -8, and -9 (Gal-3, Gal-8, and Gal-9) recognize damaged pathogen-conta
Externí odkaz:
https://doaj.org/article/bb529b2bbf75461d932dc89cb0aeb02a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Externí odkaz:
https://doaj.org/article/d05cf62381f54a26b45ba06ec123fda4
Autor:
Allison R Wagner, Chi G Weindel, Kelsi O West, Haley M Scott, Robert O Watson, Kristin L Patrick
Publikováno v:
eLife, Vol 11 (2022)
To mount a protective response to infection while preventing hyperinflammation, gene expression in innate immune cells must be tightly regulated. Despite the importance of pre-mRNA splicing in shaping the proteome, its role in balancing immune outcom
Externí odkaz:
https://doaj.org/article/6d3c3ed1193744ab8bd751412b25e522
Autor:
Katherine M Littlefield, Renée O Watson, Jennifer M Schneider, Charles P Neff, Eiko Yamada, Min Zhang, Thomas B Campbell, Michael T Falta, Sarah E Jolley, Andrew P Fontenot, Brent E Palmer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010359 (2022)
As of January 2022, at least 60 million individuals are estimated to develop post-acute sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While elevated levels of SARS-CoV-2-specific T ce
Externí odkaz:
https://doaj.org/article/7e3104f8b8854e44aae8079bdfe996d1
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/1815dc80a94a4fd98bdc418b12aa20a1
Publikováno v:
Healthcare, Vol 11, Iss 1, p 38 (2022)
Physicians are required to move and manipulate equipment to achieve motor tasks such as surgical operations, endotracheal intubations, and intravenous cannulation. Understanding how movements are generated allows for the analysis of performance, skil
Externí odkaz:
https://doaj.org/article/38de8fe26c684e9ea303b902d6c62004
Autor:
Krystal J Vail, Bibiana Petri da Silveira, Samantha L Bell, Noah D Cohen, Angela I Bordin, Kristin L Patrick, Robert O Watson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009888 (2021)
Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known about how intracellular R. equi is sensed
Externí odkaz:
https://doaj.org/article/2ac9b5fc418b491eb0a4f4d8c3eba144