Zobrazeno 1 - 10 of 63 pro vyhledávání: '"O V, Shablykin"'
1
Reactions of New N-(2,2-Dichloro-1-cyanoethenyl)amides with Aliphatic Amines
Autor: Volodymyr Brovarets, O. V. Shablykin, S. A. Chumachenko
Publikováno v: Russian Journal of General Chemistry. 91:1607-1612
Abstract The reaction of the newly synthesized N-(2,2-dichloro-1-cyanoethenyl)prop-2-enamide and 4-chloro-N-(2,2-dichloro-1-cyanoethenyl)butanamide with methylamine or dimethylamine gave rise to previously unknown 5-amino-1,3-oxazole-4-carbonitriles.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::370c5355ec40f4c7dcab086508721cad
https://doi.org/10.1134/s1070363221090012
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2
New 4-iminohydantoin sulfamide derivatives with antiviral and anticancer activity
Autor: Yurii Kornii, Volodymyr Brovarets, O. V. Shablykina, O. V. Shablykin
Publikováno v: Ukr. Bioorg. Acta 2021, Vol. 16, N1. 16:10-17
A number of sulfamides were obtained by reaction of (5-(dichloromethylene)-2-oxoimidazolidin-4-ylidene)sulfamoyl chloride with anilines, benzylamines, Boc-protected piperazine, methylalylamine, and amino acids methyl esters with primary and secondary
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d273a2497b332010f53fa8d25d4f706
https://doi.org/10.15407/bioorganica2021.01.010
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3
New Heterocyclization Reactions of N′-Substituted N-(2,2-Dichloro-1-cyanoethenyl)ureas with Aliphatic Amines
Autor: S. A. Chumachenko, Volodymyr Brovarets, Eduard B. Rusanov, O. V. Shablykin, Yu. E. Kornii
Publikováno v: Russian Journal of General Chemistry. 91:966-970
The reaction of substituted 3,3-dichloroprop-2-enenitriles containing an N-methylurea or N,N-dimethylurea residue in the second position with secondary aliphatic amines gives rise to previously unknown 2,5-bis(alkylamino)-1,3-oxazole-4-carbonitriles.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ce449512a799d4ea214a9c85def56ee
https://doi.org/10.1134/s1070363221060025
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4
Synthesis of New 1Н-Pyrrolo[3,4-с]pyridine-1,3(2Н)-diones
Autor: S. A. Chumachenko, S. V. Klyuchko, Volodymyr Brovarets, O. V. Shablykin
Publikováno v: Russian Journal of General Chemistry. 91:348-356
A method for the synthesis of a series of new substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones was proposed based on the Diels–Alder type reaction of 4-methoxy-1,3-oxazoles with maleimide derivatives.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::995e417fc2e3a2530a54c50563ab0c7d
https://doi.org/10.1134/s1070363221030026
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5
3-Hetarylisocoumarins in the synthesis of 1-functionalized 3-hetarylisoquinolines
Autor: O. V. Shablykina, V. S. Moskvina, Artem S. Konovalenko, O. V. Shablykin, Volodymyr Brovarets, Andriy V. Kozytskiy
Publikováno v: Chemistry of Heterocyclic Compounds. 56:1021-1029
A convenient method was developed for the synthesis of novel isoquinolin-1(2H)-ones, 1-chloroisoquinolines, and 1-aminoisoquinolines with a heterocyclic substituent in position 3 via a recyclization of 3-hetarylisocoumarins with (NH4)2CO3. 1-Aminoiso
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a4302d623624e71c0f06c524a4af3e5
https://doi.org/10.1007/s10593-020-02769-3
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6
5-Substituted N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamides as xanthine oxidase inhibitors
Autor: Oksana V. Muzychka, Andriy I. Vovk, Volodymyr Brovarets, O. V. Shablykin, Olexandr Kobzar
Publikováno v: Ukr. Bioorg. Acta 2020, Vol. 15, N1. 15:20-25
Synthetic 6-substituted purine derivatives are known to exhibit diverse bioactivity. In this paper, a series of N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamide derivatives were synthesized and evaluated in vitro against xanthine oxidase, an enzyme of pur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::741d0208c2a978fb72b31b0cd52f76d7
https://doi.org/10.15407/bioorganica2020.01.020
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8
Synthesis of New 2-(Oxiran-2-yl)-1,3-oxazoles
Autor: O. V. Shablykin, M. A. Volosheniuk, Volodymyr Brovarets
Publikováno v: Russian Journal of General Chemistry. 88:1542-1545
Reaction of 2-chloro-N-(2,2-dichloro-1-cyanovinyl)acetamide with dimethylamine gave 5-(dimethylamino)-2-[(dimethylamino)methyl]-1,3-oxazole-4-carbonitrile, where aliphatic dimethylamino group was regioselectively alkylated with iodomethane. The resul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fc60378b32612fc74dbc443927118e4
https://doi.org/10.1134/s1070363218070307
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