Zobrazeno 1 - 8
of 8
pro vyhledávání: '"O S, Kinsman"'
Autor:
G. L. Patrick, O. S. Kinsman
Publikováno v:
European Journal of Medicinal Chemistry. 31:615-624
Summary A series of novel aza- d --homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and te
Autor:
J. W. Lester, Phillips W. Robbins, O. S. Kinsman, W. A. Fonzi, Neil A. R. Gow, Trevor D. Chapman, Alistair J. P. Brown
Publikováno v:
Proceedings of the National Academy of Sciences. 91:6216-6220
In the dimorphic fungus Candida albicans, the CHS2 gene encodes a chitin synthase that is expressed preferentially in the hyphal form. Gene disruption of CHS2 in this diploid asexual fungus was achieved by the "ura-blaster" protocol described for Sac
Autor:
G. L. Patrick, O. S. Kinsman
Publikováno v:
ChemInform. 27
Summary A series of novel aza- d --homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and te
Autor:
O. S. KINSMAN, P. A. CHALK, H. C. JACKSON, R. F. MIDDLETON, A. SHUTTLEWORTH, B. A. M. RUDD, C. A. JONES, H. M. NOBLE, H. G. WILDMAN, M. J. DAWSON, ET AL. ET AL.
Publikováno v:
ChemInform. 29
Publikováno v:
The Journal of eukaryotic microbiology. 41(5)
Publikováno v:
British journal of experimental pathology. 66(3)
The relative virulence of pairs of staphylococci differing in resistance plasmid content has been studied using the neonatal mouse weight gain test. Both clinical and laboratory strains were used which had undergone genetic manipulation, either curin
Autor:
O S Kinsman, A E Collard
Publikováno v:
Infection and immunity. 53(3)
The hormonal status of rats affected vaginal infection with Candida albicans. Four hours after infection viable counts were higher and germ tubes were longer in those animals in estrous than in other animals. However, the infection was not maintained
Publikováno v:
Antimicrobial agents and chemotherapy. 30(5)
Rats in pseudoestrous were treated subcutaneously with ketoconazole at 25 mg/kg twice a day. In both uninfected and infected rats ketoconazole inhibited the cornification of the vaginal epithelium. Thus, ketoconazole, in addition to having an antifun