Zobrazeno 1 - 10
of 13
pro vyhledávání: '"O N, Vorontsova"'
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 50-55 (2023)
Background. Cyclo-L-prolylglycine (CPG) was designed and synthesized at the V.V. Zakusov as a topological analogue of the classical nootrop piracetam and was further identified as an endogenous compound. Previously, the nootropic effect of CPG was
Externí odkaz:
https://doaj.org/article/c9034e386a724e5da60cea30e5df46cb
Autor:
Tatiana A Gudasheva, K N Koliasnikova, P. Yu. Povarnina, S. B. Seredenin, A.G. Alyaeva, O. N. Vorontsova
Publikováno v:
Doklady. Biochemistry and biophysics. 493(1)
Previously we have shown that the neuropeptide cycloprolylglycine is an endogenous positive modulator of AMPA receptors and assumed that the pharmacological effects of CPG are associated with the brain neurotrophic factor. In this paper, we have firs
Autor:
O. N. Vorontsova, I. A. Batyrev
Publikováno v:
RADIO COMMUNICATION TECHNOLOGY. :41-53
Autor:
Tatiana A Gudasheva, O. N. Vorontsova, A. G. Mezhlumyan, P.Yu. Povarnina, A.V. Tarasiuk, S.B. Seredinin, S. V. Nikitin, N. M. Sazonova, T. A. Antipova, I. O. Logvinov
Publikováno v:
Problems Of Biological, Medical And Pharmaceutical Chemistry. 22
Autor:
E. K. Boon-Niermeijer, A. P. van den Berg, O. N. Vorontsova, I. Yu. Malyshev, L. A. Bayda, F. A. C. Wiegant
Publikováno v:
Adaptive Medicine. 4:233-244
The main aim of the studies presented in this paper was to evaluate whether standardized extracts from the plant adaptogens Eleutherococcus senticosus (SHE-3) and Rhodiola rosea (SHR-5) were able to enhance adaptive resistance during chronic stress.
Autor:
Anton A. Tonshin, O. N. Vorontsova, Lev S. Yaguzhinsky, Alexey A. Selin, N. V. Lobysheva, Ya. R. Nartsissov
Publikováno v:
Bulletin of Experimental Biology and Medicine. 153:44-47
Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Pr
Autor:
I. P. Levshina, Alexander Yakovlev, M. G. Ayarapetyanz, Mikhail V. Onufriev, M. Yu. Stepanichev, N. A. Lazareva, O. N. Vorontsova, Natalia V. Gulyaeva
Publikováno v:
Neurochemical Journal. 1:86-92
Chronic stress causes changes in neuroplasticity that are accompanied by structural changes in the neocortex and hippocampus. In this study, parameters of oxidative stress and apoptosis were investigated in different areas of rat brains subjected to
Publikováno v:
Scopus-Elsevier
Dipeptide mimetic of the nerve growth factor (NGF) loop 4, hexamethylenediamide bis-(N-monosuccinyl-glutamyl-lysine) (GK-2), was synthesized at the V.V. Zakusov Scientific Research Institute of Pharmacology of the Russian Academy of Medical Sciences.
Publikováno v:
Bulletin of experimental biology and medicine. 151(6)
An intraperitoneal injection of GK-2 (dipeptide mimetic of nerve growth factor, 0.01-5.00 mg/kg) 24 h before the adverse exposure reduced the severity of haloperidol-induced catalepsy in rats. This agent retained the activity after oral administratio
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 93(4)
Opiate addiction is accompanied by long-term structural and functional changes in brain regions persisting during abstinence, this status being an experimental model of the aberrant neuroplasticity. Nitric oxide is known to be involved in mechanisms