Zobrazeno 1 - 10
of 24
pro vyhledávání: '"O M Z Howard"'
Autor:
J Chen, N M Dunlop, Jiaqi Huang, Y Gao, O M Z Howard, X-w Bian, Wanghua Gong, Keqiang Chen, Ji Ming Wang
Publikováno v:
British Journal of Cancer
Background: The G-protein-coupled formylpeptide receptor (FPR) that mediates chemotaxis of phagocytic leucocytes induced by bacterial and host-derived chemotactic peptides is selectively expressed by highly malignant human gliomas and contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c87b9b84c9181a3d413024a77c88b65
https://doi.org/10.1038/sj.bjc.6605591
https://doi.org/10.1038/sj.bjc.6605591
Publikováno v:
Annals of the New York Academy of Sciences. 917:19-28
Opioids are known to suppress a number of elements of the immune response, including antimicrobial resistance, antibody production, and delayed-type hypersensitivity. Phagocytic cells may be particularly susceptible to opioid administration, since re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdfa26c939eb7ceaa404c370c3fae6f
https://doi.org/10.1111/j.1749-6632.2000.tb05369.x
https://doi.org/10.1111/j.1749-6632.2000.tb05369.x
Publikováno v:
Immunological Reviews. 177:68-78
"... It is likely that the leukocyte granulations are in fact secretory products, which the cell dissolves and spreads to the environment as needed", Paul Ehrlich, 1900. Neutrophil granules have long been recognized as mediators of innate host defens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f6f92f955a4cf646c0b0921a1d73e3d
https://doi.org/10.1034/j.1600-065x.2000.17702.x
https://doi.org/10.1034/j.1600-065x.2000.17702.x
Autor:
Qian Chen, Oleg Chertov, S. N. Bykovskaia, O. M. Z. Howard, D. Yang, J. I. Shogan, M. Anderson, J. M. Schröder, M. J. Buffo, Ji Ming Wang, Joost J. Oppenheim
Publikováno v:
Science. 286:525-528
Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human β-defensins are also chemotactic for immature dendritic cells and memory T cells. Human β-defensin was selectively chemotact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea131c5c0bfaa8f1120d8e91ad84edb3
https://doi.org/10.1126/science.286.5439.525
https://doi.org/10.1126/science.286.5439.525
Autor:
O. M. Z. Howard, B. Erlichman
Publikováno v:
Cytokine. 11:476-484
Tumour necrosis factor receptor (TNFR) superfamily members play critical roles in the regulation of cell proliferation and death. One member of the TNFR superfamily, CD27, is unique because it is the only covalently linked homodimer in the family. CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d30e76af9d50fdd76af87dc8d0e70f7
https://doi.org/10.1006/cyto.1998.0449
https://doi.org/10.1006/cyto.1998.0449
Publikováno v:
Journal of Clinical Immunology. 19:280-292
Despite the youth of the chemokine field, many antagonists of chemokine function have already been identified and tested at the preclinical level. These include neutralizing antibodies, peptidyl and non-peptidyl antagonists and non-specific immunosup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63cfc5210e6160de10ea0554c78aae2
https://doi.org/10.1023/a:1020587407535
https://doi.org/10.1023/a:1020587407535
Autor:
Jim A. Turpin, J. J. Oppenheim, Michael Grimm, William G. Rice, Christopher J. Michejda, Robert Blumenthal, Nadya I. Tarasova, O. M. Z. Howard, Thomas Korte
Publikováno v:
Journal of Leukocyte Biology. 64:6-13
The intersection of the HIV and the chemokine fields began with the observation that HIV entry into cells could be blocked by certain chemokines. Subsequent work showed that HIV entry is dependent on the presence of specific chemokine receptors. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09092bdeabb1cc65b28511ceb0956685
https://doi.org/10.1002/jlb.64.1.6
https://doi.org/10.1002/jlb.64.1.6
Autor:
Michael Grimm, J. H. Resau, Hydar Ali, Ricardo M. Richardson, Adit Ben-Baruch, Dennis D. Taub, O. M. Z. Howard, Joost J. Oppenheim, Ralph Snyderman, Ji Ming Wang
Publikováno v:
The Journal of Experimental Medicine
An intact chemotactic response is vital for leukocyte trafficking and host defense. Opiates are known to exert a number of immunomodulating effects in vitro and in vivo, and we sought to determine whether they were capable of inhibiting chemokine-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab239bf82502a00c1fa6153baf6a4f24
http://europepmc.org/articles/PMC2212445
http://europepmc.org/articles/PMC2212445
Autor:
Hallgeir Rui, Robert A. Kirken, M. Kawamura, Maria Grazia Malabarba, John J. O'Shea, O. M. Z. Howard, William L. Farrar
Publikováno v:
Cytokine. 7:689-700
A number of cytokines and growth factors use the JAK-STAT pathway to signal from the cell membrane to the nucleus. While homodimerizing cytokine receptors may transmit signal via a single form of JAK (i.e. growth hormone receptors), several multicomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4eb2050b9cecb7ad1f9db8146094230
https://doi.org/10.1006/cyto.1995.0081
https://doi.org/10.1006/cyto.1995.0081
Publikováno v:
Biochemical Journal. 306:217-224
The structural domains of interleukin-2 receptor beta (IL-2R beta) were examined, characterizing the protein domains, associated phosphoproteins and nuclear complexes of IL-2-induced signal transduction. A series of IL-2R beta cytoplasmic deletion mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83ceb5f7b15253c12f79000874bf0b2
https://doi.org/10.1042/bj3060217
https://doi.org/10.1042/bj3060217