Zobrazeno 1 - 10
of 13
pro vyhledávání: '"O L Stone"'
Autor:
O L Stone, Harold A. Chapman
Publikováno v:
Biochemical Journal. 230:109-116
Human and mouse macrophages release a fibrinolytic inhibitor after stimulation by endotoxin in vitro. The released mouse inhibitor was indistinguishable in size by molecular-sieve chromatography from an intracellular form (approx. 50 kDa), and both i
Publikováno v:
Journal of Clinical Investigation. 73:806-815
Fibrin deposition is prominent in the histopathology of a number of inflammatory lung diseases. Plasmin, activated locally in the lung, can degrade not only this fibrin but potentially structural proteins important to normal lung architecture. Becaus
Autor:
Harold A. Chapman, O L Stone
Publikováno v:
Journal of Clinical Investigation. 74:1693-1700
Elastin is an extracellular matrix protein critical to the normal structure and function of human lung. Recently reported data indicate that live human alveolar macrophages can degrade purified elastin in vitro. In this study, we directly compared th
Publikováno v:
The Journal of Immunology. 142:208-216
When whole serum C is activated by cobra venom factor complexes (CoFBb), paroxysmal nocturnal hemoglobinuria (PNH) III E (the most C-sensitive type) are hemolyzed, but normal and PNH II E (the intermediately sensitive type) are not. Previous studies
Publikováno v:
The Journal of clinical investigation. 75(6)
Both fibrin and tissue macrophages are prominent in the histopathology of chronic inflammatory pulmonary disease. We therefore examined the procoagulant activity of freshly lavaged human alveolar macrophages in vitro. Intact macrophages (5 X 10(5) ce
Autor:
R L, Warters, O L, Stone
Publikováno v:
Radiation research. 98(2)
The sedimentation coefficient and buoyant density of mononucleosomes from the replicating chromatin of heated (45 degrees) and unheated HeLa cells were determined. It was observed that both physical parameters were the same (S = 10.8 and p = 1.165 g/
Autor:
H A, Chapman, O L, Stone
Publikováno v:
The American review of respiratory disease. 132(3)
Alveolar macrophages are intimately involved with fibrin during the course of acute and chronic inflammatory processes in the lung. In this study, the capability of macrophages to impede fibrinolysis was investigated. Human alveolar macrophages obtai
Publikováno v:
British journal of haematology. 71(2)
Vitronectin is a plasma glycoprotein that has regulatory activity in the complement and the coagulation systems, in cell-cell and cell-substrate interactions, and in monocyte/macrophage function. Because of its potential to participate in several of
Publikováno v:
The American review of respiratory disease. 133(3)
Fibrin deposition is prominent in the histopathologic features of chronic interstitial lung disease. Human alveolar macrophages can potentially modulate this process because normal macrophages synthesize and express the initial enzymes of both coagul
Autor:
R L, Warters, O L, Stone
Publikováno v:
Radiation research. 96(3)
The incorporation of radioactivity into HeLa cell polypeptides and DNA after exposure to 45 degrees C heating for 15 min was measured by continuous exposure to radiolabeled precursors. Both polypeptide and DNA synthesis were inhibited by thermal shoc