Zobrazeno 1 - 10
of 14
pro vyhledávání: '"O L Francone"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 4, Pp 813-822 (1997)
Human lecithin:cholesterol acyltransferase (LCAT) is a key enzyme in the plasma metabolism of cholesterol and is postulated to participate in a physiologic process called reverse cholesterol transport. We have used transgenic mice expressing the huma
Externí odkaz:
https://doaj.org/article/a92fa45876ea4a619ecc8f6de3f9f4d8
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 7, Pp 1609-1615 (1996)
Mutagenesis was carried out in human lecithin:cholesterol acyltransferase (LCAT) to generate mutants with stop codons at positions corresponding to amino acids 315, 341, 359, 375, 388, 394, and 398 of the 416-amino acid sequence of the mature enzyme
Externí odkaz:
https://doaj.org/article/69ce2ac8488e4e85a84496af93a386db
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 6, Pp 1268-1277 (1996)
The effects of cholesteryl ester transfer protein (CETP) on the distribution of apolipoprotein (apo) A-I between high density lipoprotein (HDL) subspecies and its impact on efflux and esterification of cell-derived cholesterol was studied in transgen
Externí odkaz:
https://doaj.org/article/0322b3a365954451b48f117eb02058ee
Publikováno v:
Journal of Clinical Investigation. 96:1440-1448
Human (Hu) lecithin-cholesterol acyltransferase (LCAT) is a key enzyme in the plasma metabolism of cholesterol. To assess the effects of increased plasma levels of LCAT, four lines of transgenic mice were created expressing a Hu LCAT gene driven by e
Autor:
K L, Hoppe, O L, Francone
Publikováno v:
Journal of lipid research. 39(5)
Human lecithin:cholesterol acyltransferase (LCAT) circulates in plasma bound to high density lipoproteins (HDL) and modulates the rate by which cholesteryl ester is transported to the liver. So far, little is known about the regulation of the express
Publikováno v:
Journal of lipid research. 36(6)
Endotoxin (LPS) administration, which mimics infection, stimulates the production of many cytokines, including TNF, that are thought to mediate the alterations in lipid metabolism that occur during infection. The aims of this study were to determine
Publikováno v:
The American journal of physiology. 263(4 Pt 1)
Triacylglycerol (TG) stored in cytoplasmic lipid droplets of hepatocytes was labeled by in vivo [1-(14)C]oleic acid injection to study the effect of a high-fat diet on its incorporation into very-low-density lipoproteins (VLDL). Compared with the con
Publikováno v:
Advances in experimental medicine and biology. 285
Autor:
O. L. Francone, C. J. Fielding
Publikováno v:
European heart journal. 11
The early metabolism of cell-derived cholesterol was followed during the interaction of normolipaemic native plasma with cultured cell monolayers labelled to high specific activity with 3H-cholesterol. Kinetic analysis indicated that initial processi
Publikováno v:
Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics ISBN: 9781468459067
Hepatic VLDL synthesis and secretion is under nutritional control, being increased 2-fold by a sucrose-rich diet. Conversely, it is decreased 2-fold by a high-fat diet (1,2), despite the fact that fat-fed rats have elevated plasma non esterified fatt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc366d14000c408612f2c7fdb89a9eb
https://doi.org/10.1007/978-1-4684-5904-3_39
https://doi.org/10.1007/978-1-4684-5904-3_39