Zobrazeno 1 - 10
of 12
pro vyhledávání: '"O L, Terekhina"'
Autor:
E. A. Smirnova, A. B. Michunskaya, O. M. Pozdnyakov, S. V. Kruglov, L. M. Belkina, Kobozeva Lp, O. L. Terekhina
Publikováno v:
Bulletin of Experimental Biology and Medicine. 159:273-277
Alloxan diabetes was modeled in August rats with high activity of the NO system and in Wistar rats, and the effects of NO system blockade (by a course treatment with L-NNA) on Langerhans islet β cells were studied in 15 days. The toxic effects of di
Autor:
H. Fred Downey, Olga P Budanova, Eugenia B. Manukhina, Denis V. Abramochkin, Elena A Smirnova, Robert T. Mallet, O L Terekhina, L. M. Belkina
Publikováno v:
Experimental Biology and Medicine. 238:1413-1420
Favorable versus detrimental cardiovascular responses to intermittent hypoxia conditioning (IHC) are heavily dependent on experimental or pathological conditions, including the duration, frequency and intensity of the hypoxia exposures. Recently, we
Autor:
A V, Goryacheva, O L, Terekhina, D V, Abramochkin, O P, Budanova, L M, Belkina, B V, Smirin, H F, Downey, I Yu, Malyshev, E B, Manukhina
Publikováno v:
Patologicheskaia fiziologiia i eksperimental'naia terapiia. 59(4)
Previously we have shown that adaptation to hypoxia (AH) is cardio- and vasoprotective in myocardial ischemic and reperfusion injury and this protection is associated with restriction of nitrosative stress. The present study was focused on further el
Publikováno v:
Patologicheskaia fiziologiia i eksperimental'naia terapiia. 59(4)
The mechanisms of the protective effect of oligonucleotides (OGN) during pathological processes are poorlyunderstood. The goal of this work was to study the effect of OGN on arrhythmias induced by myocardial ischemia and reperfusion, and the HSP70 le
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 99(11)
Previously, we have shown that nitric oxide (NO) plays an important role in the pathogenesis of alloxan diabetes (ALD). In this study in August rats, with the congenital increased activity of NO, and in Wistar rats was induced ALD (130 mg/kg, p/c) an
Autor:
E A, Smirnova, O L, Terekhina, D D, Matzievski, T A, Antipova, L P, Kobozeva, A B, Michunskaya, O M, Pozdnyakov, S V, Kruglov, L Yu, Bakhtina
Publikováno v:
Patologicheskaia fiziologiia i eksperimental'naia terapiia. (1)
We have previously shown that the innate increased activity of the NO- system, typical for the August rats, increases vulnerability to alloxane diabetes (ALD). The purpose of this study was to investigate the effect of ALD on the cardiovascular syste
Autor:
H. F. Downey, Anna V. Goryacheva, Robert T. Mallet, O L Terekhina, Eugenia B. Manukhina, L. M. Belkina
Publikováno v:
The FASEB Journal. 28
Publikováno v:
Bulletin of experimental biology and medicine. 154(5)
We studied the effects of N(w)-nitro-L-arginine (L-NNA), a nonselective inhibitor of NO synthases, on the severity of type 1 diabetes mellitus induced by subcutaneous injection of 130 mg/kg alloxan in August rats with high activity of NO system and i
Publikováno v:
The FASEB Journal. 27
Autor:
M. A. Usacheva, E. A. Smirnova, L. M. Belkina, S. V. Kruglov, V. A. Saltykova, O. L. Terekhina
Publikováno v:
Bulletin of experimental biology and medicine. 150(3)
Similar degree of glycemia (28-31 mmol/liter) and similar mortality (37-42%) were revealed in August rats exhibiting enhanced activity of NO system and in Wistar rats 3 weeks after alloxan treatment. Under conditions of myocardial ischemia caused by