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Proatherogenic modification of LDL by surface-bound myeloperoxidase

Autor: Alexej V. Sokolov, Vadim B. Vasilyev, O. L. Runova, I. V. Gorudko, Sergej N. Cherenkevich, Valeria A. Kostevich, Oleg M. Panasenko

Publikováno v: Chemistry and Physics of Lipids. 180:72-80

One of the factors promoting oxidative/halogenating modification of low-density lipoproteins (LDL) is myeloperoxidase (MPO). We have shown previously that MPO binds to the LDL surfaces. The LDL–MPO complex is uncoupled in the presence of peptide EQ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ad1879a43304744148bf5f3e27814a
https://doi.org/10.1016/j.chemphyslip.2014.02.006

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Familial Alzheimer’s disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts

Autor: Michael P. Vitek, O. L. Runova, A. L. Schwarzman, S. V. Sarantseva, E. I. Talalaeva

Publikováno v: Biophysics. 55:760-764

Experimental evidence has been obtained that mutations in the presenilin 1 (PS1) gene in familial Alzheimer’s disease can lead to the disturbance of cell adhesion in model cell cultures. It was shown that, in L fibroblasts of mice with stable expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96c0308a8ecb3d796cef21188e26a430
https://doi.org/10.1134/s0006350910050131

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Degeneration of growth cones in a culture of embryonic neurons of mouse with presenilin 1 knockout

Autor: O. L. Runova, E. I. Talalaeva, S. V. Sarantseva, A. L. Shwartsman, K. V. Solovyov, Michael P. Vitek

Publikováno v: Biophysics. 53:550-554

A comparative study of growth cone morphology in cultured embryonic neurons derived from wild type PS 1(+/+) and knockout PS 1(-/-) mice has been performed. Growth cones from wild type PS 1(+/+) mice were well spread and usually formed radially conti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abda6192fe5fbe0f42441a5b7bf671ff
https://doi.org/10.1134/s0006350908060158

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Identification of leukocyte cationic proteins that interact with ceruloplasmin

Autor: E. T. Zakharova, K. V. Ageeva, Alexey V. Sokolov, Vadim B. Vasilyev, M. O. Pulina, O. L. Runova

Publikováno v: Biochemistry (Moscow). 72:872-877

Proteins from leukocytes were investigated for their ability to interact with ceruloplasmin (Cp), a copper-containing glycoprotein of human plasma. Extract from leukocytes was subjected to affinity chromatography on Cp-Sepharose, after which proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7238d78693214661e172e61fd9628302
https://doi.org/10.1134/s0006297907080093

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Presenilin 1 expression on the cell surface in motile polarized cells

Autor: S. V. Sarantseva, Michael P. Vitek, O. L. Runova, Yu. A. Tatishcheva, E. I. Talalaeva, A. L. Schwartsman

Publikováno v: Biophysics. 51:740-743

Most cases of early-onset familial Alzheimer’s disease are caused by mutations in the presenilin 1 gene. Nonetheless, the function of presenilin 1 are not yet completely understood. It was shown that endogenous presenilin 1, as well as the adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3608b8399fa461873c1e9cfc5e41447c
https://doi.org/10.1134/s0006350906050125

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Identification and isolation from breast milk of ceruloplasmin-lactoferrin complex

Autor: A. S. Susorova, E. T. Zakharova, N. I. Kolodkin, M. O. Pulina, Alexey V. Sokolov, Vadim B. Vasilyev, O. L. Runova

Publikováno v: Biochemistry (Moscow). 71:160-166

The presence of a complex of the copper-containing protein ceruloplasmin (Cp) with lactoferrin (Lf) in breast milk (BM) is shown for the first time. In SDS-free polyacrylamide gel electrophoresis (PAGE), electrophoretic mobility of Cp in BM is lower

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4d7a76666c43e44d6e282a4650789a
https://doi.org/10.1134/s0006297906020076

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Production and characterization of a recombinant ligand-binding domain of the human low-density lipoprotein receptor

Autor: M. Yu. Mandelshtam, O. L. Runova, V. I. Golubkov, V. S. Gaitskhoki

Publikováno v: Bulletin of Experimental Biology and Medicine. 123:159-162

Two plasmids carrying the cDNA fragment of human low-density lipoprotein receptor coding for its ligand-binding domain are constructed. The ligand-binding domain of the receptor composed of fused and individual polypeptides is purified and characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::673a43dcf28e17484b9237921dac4f4c
https://doi.org/10.1007/bf02766440

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[Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts]

Autor: A L, Shvartsman, S V, Sarantseva, O L, Runova, E I, Talalaeva, M P, Vitek

Publikováno v: Biofizika. 55(5)

Experimental evidence has been obtained that mutations in the presenilin 1 (PS1) gene in familial Alzheimer's disease can lead to the disturbance of cell adhesion in model cell cultures. It was shown that, in L fibroblasts of mice with stable express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fae26973a97a638539ec6743c990f896
https://pubmed.ncbi.nlm.nih.gov/21033353

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[Degeneration of growth cones in a culture of embryonic neurons of mouse with presenilin 1 gene knockout]

Autor: A L, Shvartsman, S V, Sarantseva, K V, Solov'ev, O L, Runova, E I, Talalaeva, M P, Vitek

Publikováno v: Biofizika. 53(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bcce909fddb23f1ae02d879b10756c3
https://pubmed.ncbi.nlm.nih.gov/19137685

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