Zobrazeno 1 - 10
of 13
pro vyhledávání: '"O K, Haffar"'
Publikováno v:
Immunology. 90:281-285
Complete activation of peripheral blood T cells requires both T-cell receptor (TCR) stimulation and CD28 costimulation. Signalling pathways associated specifically with CD28 are not well understood, however, because ligation of CD28 in the absence of
Publikováno v:
The Journal of Immunology. 156:2324-2330
We have investigated the effect of exogenous IL-7 on replication of HIV-1 in PBMCs isolated from asymptomatic, chronically infected donors. We show that IL-7 induced virus replication and increased proviral DNA levels in CD8- PBMC cultures. IL-7 also
Autor:
S B Kanner, O K Haffar
Publikováno v:
The Journal of Immunology. 154:2996-3005
One consequence of HIV type 1 (HIV-1) infection is the gradual loss of responsiveness of T lymphocytes to Ags both in vitro and in vivo. It has been suggested that the underlying mechanism that contributes to this T cell dysfunction before CD4+ cell
Autor:
O K, Haffar, S, Popov, L, Dubrovsky, I, Agostini, H, Tang, T, Pushkarsky, S G, Nadler, M, Bukrinsky
Publikováno v:
Journal of molecular biology. 299(2)
Replication of HIV-1 in non-dividing and slowly proliferating cell populations depends on active import of the viral pre-integration complex (PIC) into the cell nucleus. While it is commonly accepted that this process is mediated by an interaction be
Publikováno v:
Virology. 180:439-441
The HIV-1 envelope glycoprotein gpl60 associates with cellular membranes via a discrete transmembrane domain. Unlike other retroviral envelope proteins, however, gp160 also forms a secondary association with the lipid bilayer mediated by one or more
Autor:
M I, Bukrinsky, O K, Haffar
Publikováno v:
Molecular medicine (Cambridge, Mass.). 4(3)
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(6)
We have investigated the effect of exogenous IL-7 on replication of HIV-1 in PBMCs isolated from asymptomatic, chronically infected donors. We show that IL-7 induced virus replication and increased proviral DNA levels in CD8- PBMC cultures. IL-7 also
Autor:
S B, Kanner, O K, Haffar
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(6)
One consequence of HIV type 1 (HIV-1) infection is the gradual loss of responsiveness of T lymphocytes to Ags both in vitro and in vivo. It has been suggested that the underlying mechanism that contributes to this T cell dysfunction before CD4+ cell
Mutagenesis of the transmembrane domain and cytoplasmic tail of human immunodeficiency virus type 1 envelope glycoprotein gp160 revealed that its intracellular transport and processing in transfected cell lines were modulated by a functional domain i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d645a5157b407bb3a4d521e9c0b96d
https://europepmc.org/articles/PMC249502/
https://europepmc.org/articles/PMC249502/
Publikováno v:
The Journal of Cell Biology
The orientation in cellular membranes of the 856 amino acid envelope glycoprotein precursor, gp160, of human immunodeficiency virus type 1 was investigated in vitro. Variants of the env gene were transcribed using the bacteriophage SP6 promoter, tran