Výsledky vyhledávání - "O J Arias-Mutis"

PPARγ as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits

Autor: Soraya L. Valles, O J Arias-Mutis, Marc Gimeno-Raga, Teresa San-Miguel, Patricia Marchio, María Dolores Mauricio, José M. Vila, Martin Aldasoro, Manuel Zarzoso, Sol Guerra-Ojeda

Publikováno v: Guerra Ojeda, Sol Marchio, Patricia Gimeno Raga, Marc Arias Mutis, Óscar J. San Miguel Díez, Teresa Valles Martí, Lilian Soraya Aldasoro Celaya, Martín Vila Salinas, José María Zarzoso Muñoz, Manuel Mauricio Aviñó, María Dolores 2021 PPARγ as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits Atherosclerosis. 2021, vol 332, pp. 16-23.
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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Background and aims Underlying mechanisms associated with vascular dysfunction in metabolic syndrome (MetS) remain unclear and can even vary from one vascular bed to another. Methods In this study, MetS was induced by a high-fat, high-sucrose diet, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536c69da77487b1949ab7ba8b3231fde
https://doi.org/10.1016/j.atherosclerosis.2021.08.006

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The administration of valproic acid exerts a protective effect by reducing the infarct size and the triggering of ventricular fibrillation in an experimental model of chronic myocardial infarction

Autor: P Genoves, O J Arias-Mutis, G Parra-Giraldo, L Such-Miquel, I Del Canto Serrano, M Zarzoso, J Ortiz-Guzman, A Alberola Aguilar, L Such-Belenguer, F J Chorro Gasco

Publikováno v: European Heart Journal. 43

Introduction In myocardial infarction there are complications associated with adverse cardiac remodeling that occurs during the fibrotic process, producing an arrhythmogenic substrate that favors the triggering of ventricular arrhythmias such as vent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0710cb485dd6878f523dbba05ff17eb0
https://doi.org/10.1093/eurheartj/ehac544.2909

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Time and frequency domain analysis of long-term heart rate variability in an experimental model of diet-induced metabolic syndrome

Autor: O J Arias-Mutis, A. Bizy, Antonio Alberola, Francisco J. Chorro, Manuel Zarzoso, Jichao Zhao, Wilson M. Lozano, Conrado J. Calvo, Luis Such-Miquel

Publikováno v: European Heart Journal. 42

Background Metabolic syndrome (MetS) is defined as the set of at least three of the following conditions: central obesity, elevation of triglycerides, decreased in high-density lipoproteins, systemic hypertension and glucose intolerance. MetS is link

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55a275c7194dcb3b87b10c86b4fe077a
https://doi.org/10.1093/eurheartj/ehab724.3227

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Endurance training increases ventricular refractoriness and wavelength of the cardiac impulse without participation of parasympathetic postganglionic neurons. A study in isolated rabbit heart

Autor: Antonio Alberola, L. Such, O J Arias-Mutis, A Rodrigo-Garcia, Manuel Zarzoso, Francisco J. Chorro, Luis Such-Miquel, G Parra, Wilson M. Lozano, Conrado J. Calvo

Publikováno v: European Heart Journal. 42

Background Endurance physical training plays a protective role in against ventricular fibrillation (VF), but the exact underlying mechanisms are not completely understood. It is well-known that modifications in myocardial ventricular properties such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3eb80e7084633cdc4bbc0622115590ba
https://doi.org/10.1093/eurheartj/ehab724.2695

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Modifications of short-term intrinsic pacemaker variability in diet-induced metabolic syndrome: a study on isolated rabbit heart

Autor: Luis Such, Antonio Alberola, Luis Such-Miquel, Patricia Genovés, Wilson M. Lozano, Conrado J. Calvo, Francisco J. Chorro, Manuel Zarzoso, José Millet, Antonio Guill, O J Arias-Mutis, Sandeep V. Pandit

Publikováno v: Journal of Physiology and Biochemistry. 75:173-183

Metabolic syndrome (MetS) describes a condition associated with multiple diseases concomitantly such as diabetes, hypertension, obesity, and dyslipidemia. It has been linked with higher prevalence of cardiovascular disease, atrial fibrillation, and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::396d0fb9a1ef1a0227b443994a2cffca
https://doi.org/10.1007/s13105-019-00667-7

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CaMKII inhibition reduces electrical activation heterogeneities caused by mechanical stretch in the myocardium

Autor: Luis Such, Antonio Alberola, Luis Such-Miquel, Patricia Genovés, F J Chorro-Gasco, Germán Parra, M Munoz, M.J Cardells, O J Arias-Mutis, Irene Del-Canto, H Martinez-Navarro, Manuel Zarzoso

Publikováno v: European Heart Journal. 41

Introduction Ca2+/calmodulin-dependant protein kinase II (CaMKII) activity in cardiomyocytes plays a crucial role in their contractility. Increased CaMKII signalling has been associated with mechanical stretch, often caused in the border zone of myoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49b8d7c1fde48c7b379941f8c6e68b33
https://doi.org/10.1093/ehjci/ehaa946.3703

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Development and Long-Term Follow-Up of an Experimental Model of Myocardial Infarction in Rabbits

Autor: Irene del Canto, Antonio Alberola, Luis Such-Miquel, Patricia Genovés, Luis Such, Francisco J. Chorro, Germán Parra, Eva Blanch, O J Arias-Mutis, Carlos Soler, Manuel Zarzoso, Ana Díaz

Publikováno v: Animals : an Open Access Journal from MDPI
Animals
Volume 10
Issue 9
Animals, Vol 10, Iss 1576, p 1576 (2020)

Simple Summary Ischemic heart disease is one of the leading causes of death. A series of processes occur during acute myocardial infarction that contribute to the development of ventricular dysfunction, with subsequent heart failure and ventricular a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be740783bbaadaa27ec8041732eadfd
http://europepmc.org/articles/PMC7552163

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P3492Carvedilol and its analogue VK-II-86 attenuate stretch-induced manifestations of mechanoelectric feedback

Autor: Francisco J. Chorro, Carlos Soler, Luis Such-Miquel, L. Such, Manuel Zarzoso, Patricia Genovés, G Parra, Antonio Alberola, L Santamaria, I Del Canto Serrano, O J Arias-Mutis

Publikováno v: European Heart Journal. 40

Background Mechanical stretch modifies Ca2+ handling and myocardial electrophysiology, favoring arrhythmogenesis. The store-overload-induced Ca2+ release (SOICR) through the ryanodine receptor (RyR2) seems to be implicated in this deleterious effect.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aeb4624c8faa7f9a0f8ef10d26a9eefc
https://doi.org/10.1093/eurheartj/ehz745.0359

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P1605Increased irregularity and spectral complexity of the intrinsic pacemaker beat-to-beat variability correlates with increased metabolic syndrome components

Autor: F J Chorro-Gasco, Patricia Genovés, Wilson M. Lozano, Conrado J. Calvo, Antonio Alberola, Luis Such-Miquel, O J Arias-Mutis, Manuel Zarzoso, Sandeep V. Pandit

Publikováno v: European Heart Journal. 40

Background Metabolic syndrome (MetS) is becoming one of the future potential leading risk factors for heart and cardiovascular disease. MetS relates to a condition associated with at least three metabolic risk factors raising risk for health diseases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99b3920484819d124e731440292d10d3
https://doi.org/10.1093/eurheartj/ehz748.0364

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P1602Basic electrophysiological modifications induced by carvedilol in unstrectched and stretched ventricular myocardium

Autor: Antonio Alberola, L. Such, Manuel Zarzoso, G Parra, J Solera, I Del Canto Serrano, Carlos Soler, O J Arias-Mutis, Luis Such-Miquel, Patricia Genovés, Francisco J. Chorro

Publikováno v: European Heart Journal. 40

Background Acute regional ventricular stretch (ARVS) is a pathophysiologic event that may occur in certain situations, originating arrhythmogenic effects through the mechanoelectrical feedback. Mechanical effects of stretch originate calcium-related

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::792e971ed20841f9ed91bc768753c5fd
https://doi.org/10.1093/eurheartj/ehz748.0361

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