Zobrazeno 1 - 10
of 11
pro vyhledávání: '"O Iu Pankov"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 115:231-234
The antiepileptic efficacy of complex of some drugs acting on different epileptic mechanisms was studied in the experiments on mice using the maximal electroshock seizure test. Combined anticonvulsant effects were evaluated by the isobolographic meth
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 116(10)
The experiments on focal penicillin-induced epileptic activity in the brain cortex (Wistar rats) and bicuculline- and thiosemicarbazide-induced seizures (Icr:Icl mice) showed that the glutapyrone possessed a significant antiepileptic activity. As pre
Autor:
M N, Karpova, S K, Germane, G, Cebers, O Iu, Pankov, V E, Klusa, G Ia, Duburs, E A, Bisenieks
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 116(9)
Experiments on male Wistar rats and Icr:Icl mice studied the influence of the novel compound--amino acid-containing 1,4-dihydropyridine derivative glutapyrone (G) on acute generalized seizures, arecoline and nicotine tremor, and 45Ca2+ uptake in brai
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 115(3)
The antiepileptic efficacy of complex of some drugs acting on different epileptic mechanisms was studied in the experiments on mice using the maximal electroshock seizure test. Combined anticonvulsant effects were evaluated by the isobolographic meth
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 114(9)
In experiments on Wistar male rats it was shown that i.p. administration of verapamil or ryodipine (1,4-dihydropyridine) 15 min before each daily injection of pentylenetetrazol (PTZ) in a subconvulsive dose 30 mg/kg during 28 days significantly delay
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(11)
To select homogeneous groups of sensitive and low-sensitive animals (male Wistar rats) for subsequent kindling experiments the animals's reaction to the threshold dose of pentylenetetrazole (PTZ) (40 mg/kg, i.p.) was defined. Rats showing convulsive
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(10)
In experiments on freely moving male Wistar rats it was shown that IOS-1.1212 (1,4-dihydropyridine) in a dose 2 and 10 mg/kg (i. p.) suppressed the penicillin-induced focal epileptic activity in cerebral cortex. Similar suppressing effect of IOS-1.12
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(9)
In experiments on freely moving male Wistar rats it was shown that nifedipine in a dose 10 mg/kg (i.p.) suppressed the penicillin-induced focal epileptic activity in cerebral cortex. A similar suppressing effect of nifedipine was shown on acute gener
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 111(4)
In experiments on freely moving Wistar rats it was shown that an intraperitoneal administration of PN 200-110 in a dose of 2 mg/kg in the period of steady epileptic activity (EpA) with regular generation of ictal discharges in penicillin--induced foc
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 110(10)
In experiments on rats it was shown that i.p. administration of finoptin (verapamil), magnesium sulfate or ryodipine (an 1,4-dihydropyridine) 15 min before each daily injection of pentylenetetrazole (PTZ) in a subconvulsive dose (30 mg/kg i.p.) signi