Zobrazeno 1 - 10
of 11
pro vyhledávání: '"O Iu, Pankov"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 115:231-234
The antiepileptic efficacy of complex of some drugs acting on different epileptic mechanisms was studied in the experiments on mice using the maximal electroshock seizure test. Combined anticonvulsant effects were evaluated by the isobolographic meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b69942d9a075e93a4a4ccc6e3fecb2c
https://doi.org/10.1007/bf00836394
https://doi.org/10.1007/bf00836394
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 116(10)
The experiments on focal penicillin-induced epileptic activity in the brain cortex (Wistar rats) and bicuculline- and thiosemicarbazide-induced seizures (Icr:Icl mice) showed that the glutapyrone possessed a significant antiepileptic activity. As pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fbbbda5be4e8a88238d1287c84f4ed8
https://pubmed.ncbi.nlm.nih.gov/8117948
https://pubmed.ncbi.nlm.nih.gov/8117948
Autor:
M N, Karpova, S K, Germane, G, Cebers, O Iu, Pankov, V E, Klusa, G Ia, Duburs, E A, Bisenieks
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 116(9)
Experiments on male Wistar rats and Icr:Icl mice studied the influence of the novel compound--amino acid-containing 1,4-dihydropyridine derivative glutapyrone (G) on acute generalized seizures, arecoline and nicotine tremor, and 45Ca2+ uptake in brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6e90946455b9cad52a1284f9fb1a9f9
https://pubmed.ncbi.nlm.nih.gov/8118003
https://pubmed.ncbi.nlm.nih.gov/8118003
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 115(3)
The antiepileptic efficacy of complex of some drugs acting on different epileptic mechanisms was studied in the experiments on mice using the maximal electroshock seizure test. Combined anticonvulsant effects were evaluated by the isobolographic meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0787549857304a09fb4767c26a2645f
https://pubmed.ncbi.nlm.nih.gov/8054599
https://pubmed.ncbi.nlm.nih.gov/8054599
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 114(9)
In experiments on Wistar male rats it was shown that i.p. administration of verapamil or ryodipine (1,4-dihydropyridine) 15 min before each daily injection of pentylenetetrazol (PTZ) in a subconvulsive dose 30 mg/kg during 28 days significantly delay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49f837ba98c8f117be0244a4f9386419
https://pubmed.ncbi.nlm.nih.gov/1477346
https://pubmed.ncbi.nlm.nih.gov/1477346
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(11)
To select homogeneous groups of sensitive and low-sensitive animals (male Wistar rats) for subsequent kindling experiments the animals's reaction to the threshold dose of pentylenetetrazole (PTZ) (40 mg/kg, i.p.) was defined. Rats showing convulsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8293c59610a35ece215177735954eb5
https://pubmed.ncbi.nlm.nih.gov/1810474
https://pubmed.ncbi.nlm.nih.gov/1810474
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(10)
In experiments on freely moving male Wistar rats it was shown that IOS-1.1212 (1,4-dihydropyridine) in a dose 2 and 10 mg/kg (i. p.) suppressed the penicillin-induced focal epileptic activity in cerebral cortex. Similar suppressing effect of IOS-1.12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87af0afb1d9b6d5d647dff1a3292e9cd
https://pubmed.ncbi.nlm.nih.gov/1804343
https://pubmed.ncbi.nlm.nih.gov/1804343
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(9)
In experiments on freely moving male Wistar rats it was shown that nifedipine in a dose 10 mg/kg (i.p.) suppressed the penicillin-induced focal epileptic activity in cerebral cortex. A similar suppressing effect of nifedipine was shown on acute gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40d60c623f8d492d29514932ca9ce0fd
https://pubmed.ncbi.nlm.nih.gov/1747472
https://pubmed.ncbi.nlm.nih.gov/1747472
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 111(4)
In experiments on freely moving Wistar rats it was shown that an intraperitoneal administration of PN 200-110 in a dose of 2 mg/kg in the period of steady epileptic activity (EpA) with regular generation of ictal discharges in penicillin--induced foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d92ea6765e939d2c823c509cd0d3649
https://pubmed.ncbi.nlm.nih.gov/1832577
https://pubmed.ncbi.nlm.nih.gov/1832577
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 110(10)
In experiments on rats it was shown that i.p. administration of finoptin (verapamil), magnesium sulfate or ryodipine (an 1,4-dihydropyridine) 15 min before each daily injection of pentylenetetrazole (PTZ) in a subconvulsive dose (30 mg/kg i.p.) signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb53c9dc461a5a305dbce8512b011e3e
https://pubmed.ncbi.nlm.nih.gov/2279078
https://pubmed.ncbi.nlm.nih.gov/2279078