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pro vyhledávání: '"O Iu, Kravtsova"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 70(2)
Afobazole pharmacokinetics was studied after the administration via different ways in rats. After oral administration, afobazole is subject to intensive biotransformation with the formation of several metabolites (M-6, M-7, and M-11). The drug and it
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 68(2)
The pharmacokinetics and biotransformation of mexidol was studied in BALB/C and C57BL/6 mice. The blood plasma contains dealkylated metabolites, and the urine contains glucuronoconjugated derivatives of the drug. The process of glucuronoconjugation m
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 67(6)
The effect of mexidol administered in a dose of 100 mg/kg (i.p.) was studied in BALB/C and C57BL/6 mice on various emotional stress models including open field test, elevated plus-maze test, and passive avoidance conditioned reflex. Upon a single adm