Zobrazeno 1 - 10
of 1 379
pro vyhledávání: '"O Hayaishi"'
Autor:
O, HAYAISHI, Y, NISHIZUKA
Publikováno v:
[Kagaku] [Science]. 31
Publikováno v:
Clinical Chemistry. 42:1984-1991
A two-site sandwich-type assay for human prostaglandin D (PGD) synthase (beta-trace) was developed with two monoclonal antibodies and using time-resolved fluorometry as the detection technique. The assay is precise (CVs < 10%), accurate, and highly s
Publikováno v:
The Journal of neuroscience, vol. 15, no. 1 Pt 1, pp. 470-476
Homogenates of chick dorsal root ganglia (DRG) and in vitro cultures of DRG neurons are known to synthesize prostaglandin (PG) D2. To specify the PGD synthase isozymes controlling PGD2 synthesis in DRG and to identify the DRG cells responsible for th
Publikováno v:
ChemInform. 22
Publikováno v:
Archives italiennes de biologie. 142(4)
(1) Prostaglandin D2 is essential for the maintenance of the sleep state. (2) The adenosine and A2A receptor system is a link between the humoral and neural mechanisms of sleep-wake regulation. (3) Prostaglandin D2 plays a crucial role in the homeost
Autor:
C T, Beuckmann, M, Lazarus, D, Gerashchenko, A, Mizoguchi, S, Nomura, I, Mohri, A, Uesugi, T, Kaneko, N, Mizuno, O, Hayaishi, Y, Urade
Publikováno v:
The Journal of comparative neurology. 428(1)
We applied high-resolution laser-scanning microscopy, electron microscopy, and non-radioactive in situ hybridization histochemistry to determine the cellular and intracellular localization of lipocalin-type prostaglandin D synthase, the major brain-d
Publikováno v:
Neurochemical research. 25(5)
Cytosolic prostaglandin (PG) E synthase was purified from human brain cortex. The N-terminal amino acid sequence, PMTLGYXNIRGL, was identical to that of the human mu-class glutathione transferase (GST) M2 subunit. Complementary DNAs for human GSTM2,
Autor:
Y, Urade, O, Hayaishi
Publikováno v:
Vitamins and hormones. 58
Prostaglandin (PG) D synthase catalyzes the isomerization of PGH2, a common precursor of various prostanoids, to produce PGD2 in the presence of sulfhydryl compounds. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, acts as a