Zobrazeno 1 - 10
of 33
pro vyhledávání: '"O G, Chakhmakhcheva"'
Publikováno v:
Bioorganicheskaia khimiia. 37(5)
A general scheme for the synthesis of ribonucleotide monomers containing alkoxymethyl group in 2'-O-position for the solid-phase phosphotriester oligonucleotide synthesis using O-nucleophilic intramolecular catalysis has been developed. In particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe9387f266834ec41763c32f16e9039e
https://pubmed.ncbi.nlm.nih.gov/22332361
https://pubmed.ncbi.nlm.nih.gov/22332361
Publikováno v:
Bioorganicheskaia khimiia. 37(2)
An efficient synthetic method for monomer ribonucleotide synthons containing 2'-O-methoxymethyl and 2'O-(p-nitrobenzyloxy)methyl groups used for oligonucleotide phosphotriester method with O-nucleophilic intramolecular catalysis at the stage of forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::099342eafb86131d2dc64fda42b6d3e1
https://pubmed.ncbi.nlm.nih.gov/21721262
https://pubmed.ncbi.nlm.nih.gov/21721262
Publikováno v:
Bioorganicheskaia khimiia. 37(2)
Conjugate the fluorescent dye 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indatsen-8-propionic acid (BODIPY) and N2,N4,N6-trimethylmelamine was obtained. It was shown that this compound in the presence of formaldehyde generates covalent cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdc1d7173d04ef0aaeded62dce6990e6
https://pubmed.ncbi.nlm.nih.gov/21721261
https://pubmed.ncbi.nlm.nih.gov/21721261
Publikováno v:
Bioorganicheskaia khimiia. 36(6)
In order to improve physicochemical and biological properties of natural oligonucleotides in particular increasing their affinity for nucleic acids, the selectivity of action and biological sustainability, several types of DNA mimics were designed. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40698c5101f052c3e6c754faf8d5a2fb
https://pubmed.ncbi.nlm.nih.gov/21317938
https://pubmed.ncbi.nlm.nih.gov/21317938
Autor:
O. G. Chakhmakhcheva, V. A. Efimov
Publikováno v:
Collection Symposium Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72298048f7e5a4a8d68fa35648c1d1f2
https://doi.org/10.1135/css200205135
https://doi.org/10.1135/css200205135
Autor:
V A, Efimov, O G, Chakhmakhcheva
Publikováno v:
Bioorganicheskaia khimiia. 25(11)
Approaches to preparing acrylamide and polyacrylamide conjugates with oligonucleotides and some peptide nucleic acid-related DNA mimics are considered. Their physicochemical properties and application to the nucleic acid analysis are discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a56a6b9be93e9f503301379c4a99ec4c
https://pubmed.ncbi.nlm.nih.gov/10645490
https://pubmed.ncbi.nlm.nih.gov/10645490
[Peptide nucleic acids and their phosphonate analogues: synthesis and hybridization characteristics]
Publikováno v:
Bioorganicheskaia khimiia. 24(9)
The synthesis of a series of DNA mimics--peptide nucleic acids, phosphonate analogues of peptide nucleic acids, and their hybrids--is described. The preparative synthesis of the corresponding monomers and the solid phase automated synthesis of oligom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::409f8016babe48bc6c98ce6ca9441f98
https://pubmed.ncbi.nlm.nih.gov/9813733
https://pubmed.ncbi.nlm.nih.gov/9813733
Publikováno v:
Bioorganicheskaia khimiia. 22(7)
To verify experimentally the molecular recognition theory, plasmids were constructed that provided the efficient synthesis of hybrid proteins composed of human calcitonin or miniproinsulin, the corresponding antisense peptides, and a histidine-rich m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04bd9d9b2467e19171b7828500698b79
https://pubmed.ncbi.nlm.nih.gov/8992955
https://pubmed.ncbi.nlm.nih.gov/8992955
Publikováno v:
Bioorganicheskaia khimiia. 22(3)
Chemicoenzymatic synthesis and cloning of a gene encoding the Fc domain of human immunoglobulin G1 were carried out. The artificial gene was expressed in Escherichia coli cells in plasmid vectors under control of a late T7 promoter. The recombinant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::511a8e8a587107a6cb14fdf2dd8d6cdc
https://pubmed.ncbi.nlm.nih.gov/8687508
https://pubmed.ncbi.nlm.nih.gov/8687508
Publikováno v:
Bioorganicheskaia khimiia. 22(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6422d361035a4fa14fe92af2f0ae54eb
https://pubmed.ncbi.nlm.nih.gov/8651962
https://pubmed.ncbi.nlm.nih.gov/8651962