Zobrazeno 1 - 10
of 34
pro vyhledávání: '"O David, Sherwood"'
Publikováno v:
Endocrinology. 149:2072-2079
The objective of this study was to determine whether stromal and/or epithelial relaxin receptor (LGR7) is required for relaxin to promote proliferation and inhibit apoptosis of stromal and epithelial cells in the mouse cervix and vagina. Tissue recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7060a6bd56a60c3e7306a66bdbe6a246
https://doi.org/10.1210/en.2007-1176
https://doi.org/10.1210/en.2007-1176
Autor:
O. David Sherwood, Hyung-Yul Lee
Publikováno v:
Biology of Reproduction. 73:790-797
Serum levels of the ovarian hormones relaxin, estrogen, and progesterone are elevated during the second half of 23-day rat pregnancy when dramatic growth of the cervix occurs. Recently, we demonstrated that relaxin contributes to cervical growth by b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda9f2b71c3ccf3ed0d37c5fe6bda36d
https://doi.org/10.1095/biolreprod.105.043984
https://doi.org/10.1095/biolreprod.105.043984
Autor:
O. David Sherwood
Publikováno v:
Annals of the New York Academy of Sciences. 1041:xxix-xxxv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1494f57c396aa60e58da0fe7d3c1089f
https://doi.org/10.1196/annals.1282.084
https://doi.org/10.1196/annals.1282.084
Autor:
Aaron J. W. Hsueh, O. David Sherwood, Jin Kumagai, Shinya Nishi, Masataka Kudo, Ross A. D. Bathgate, Koji Nakabayashi, Sheau Yu Teddy Hsu
Publikováno v:
Molecular and Cellular Endocrinology. 202:165-170
The insulin/relaxin peptide family includes insulin, IGFs, relaxin1-3, INSL3/RLF, INSL4, INSL5/RIF2 and INSL6/RIF1, many without functional characterization. Based on analysis of transgenic phenotypes and phylogenetic profiling, we have discovered th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d31ceafc3ee7cae759df5fda1bd20d
https://doi.org/10.1016/s0303-7207(03)00078-9
https://doi.org/10.1016/s0303-7207(03)00078-9
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 283:R349-R355
Administration of the ovarian hormone relaxin to nonpregnant rats vasodilates the renal circulation comparable to pregnancy. This vasodilation is mediated by endothelin (ET), the ETB receptor, and nitric oxide. Furthermore, endogenous relaxin mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3661f74d8660788d4a26855c582e1d52
https://doi.org/10.1152/ajpregu.00635.2001
https://doi.org/10.1152/ajpregu.00635.2001
Autor:
O. David Sherwood, Kimio Bamba, Tetsuya Kohsaka, Hidenari Takahara, Eimei Sato, Hiroshi Sasada
Publikováno v:
Journal of Reproduction and Development. 47:197-204
The purpose of this investigation was to examine whether boar spermatozoa possess specific binding sites for relaxin and to examine what effects relaxin actually exerts on their motility characteristics. Boar spermatozoa were collected from cauda epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb476e8627a8c278395f85d7610f3cd1
https://doi.org/10.1262/jrd.47.197
https://doi.org/10.1262/jrd.47.197
Publikováno v:
Endocrinology. 139:867-873
Relaxin plays a major role in promoting the growth and softening of the cervix that occurs during the second half of pregnancy in the rat. There is limited evidence that prostaglandins play a role in cervical softening in mammalian species. According
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d483d7c45a1b631df0852f6be0fb3e
https://doi.org/10.1210/endo.139.3.5843
https://doi.org/10.1210/endo.139.3.5843
Autor:
J. Larry Jameson, Roger D. Shanks, Daryl D. Meling, Lijuan Yao, Paul S. Cooke, O. David Sherwood
The study objective was to determine whether stromal and/or epithelial estrogen receptor-alpha (ERalpha) is required for relaxin to promote proliferation of stromal and epithelial cells in the mouse cervix. Four types of tissue recombinants were prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82eb601cef49d9afb59711c08cfbf2a2
https://europepmc.org/articles/PMC2875817/
https://europepmc.org/articles/PMC2875817/
Relaxin and estrogen are secreted by the ovary during the second half of pregnancy in rats and mice. Relaxin promotes marked growth of the lower reproductive tract in both species. Relaxin promotes accumulation of epithelial and stromal cells in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a60e84ac6081ceb3b1b5690bd068e5
https://europepmc.org/articles/PMC2743517/
https://europepmc.org/articles/PMC2743517/
Publikováno v:
Pharmacological reviews. 58(1)
Although the hormone relaxin was discovered 80 years ago, only in the past 5 years have the receptors for relaxin and three other receptors that respond to related peptides been identified with all four receptors being G-protein-coupled receptors. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaca1877c9348863a3ecf77e55581a3
https://pubmed.ncbi.nlm.nih.gov/16507880
https://pubmed.ncbi.nlm.nih.gov/16507880