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Acid suppression does not change respiratory symptoms in children with asthma and gastro-oesophageal reflux disease

Autor: L Sandvik, O. Closs, Beint S. Bentsen, K C L Carlsen, Groa B. Johannesdottir, M. Handeland, Ketil Størdal, H. K. Holm, Per Kristian Knudsen

Background: Epidemiological studies have shown an association between gastro-oesophageal reflux disease (GORD) and asthma, and oesophageal acid perfusion may cause bronchial constriction. However, no causative relation has been proven. Aim: To assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2414974c8dc95dfceab3e57d906d51e6
https://europepmc.org/articles/PMC1720585/

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Effect of aluminium hydroxide and meningococcal serogroup C capsular polysaccharide on the immunogenicity and reactogenicity of a group B Neisseria meningitidis outer membrane vesicle vaccine

Autor: E, Rosenqvist, E A, Høiby, G, Bjune, A, Aase, A, Halstensen, A K, Lehmann, J, Paulssen, J, Holst, T E, Michaelsen, H, Nøkleby, L O, Frøholm, O, Closs

Publikováno v: Developments in biological standardization. 92

Three different formulations of an outer membrane vesicle (OMV) vaccine against group B meningococcal disease have been prepared and tested for immunogenicity and reactogenicity in adult volunteers. The vaccines were prepared with or without aluminiu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f223f88ffa1bc8f6ee953177b3d490de
https://pubmed.ncbi.nlm.nih.gov/9554288

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Design of clinical trials with an outer membrane vesicle vaccine against systemic serogroup B meningococcal disease in Norway

Autor: G, Bjune, O, Closs, L O, Frøholm, J K, Grønnesby, E A, Høiby, H, Nøkleby

Publikováno v: NIPH annals. 14(2)

An outer membrane vesicle vaccine against acute, systemic disease caused by meningococci of serogroup B has been developed. The vaccine has been tested consecutively in phase I and phase II clinical trials including more than 5000 volunteers. These t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7f778c5ef3956838ca5d7440435f713
https://pubmed.ncbi.nlm.nih.gov/1812439

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Human antibody responses after vaccination with the Norwegian group B meningococcal outer membrane vesicle vaccine: results from ELISA studies

Autor: E, Rosenqvist, E A, Høiby, G, Bjune, K, Bryn, O, Closs, B, Feiring, A, Klem, H, Nøkleby, L O, Frølm

Publikováno v: NIPH annals. 14(2)

Antibody responses after vaccination with three different formulations of a new meningococcal group B outer membrane vesicle (OMV) vaccine have been studied with the ELISA technique using four different antigens. Sera from about 1200 vaccinees partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc4902f38df03afc4fa969c79b75355d
https://pubmed.ncbi.nlm.nih.gov/1687481

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Results of an efficacy trial with an outer membrane vesicle vaccine against systemic serogroup B meningococcal disease in Norway

Autor: G, Bjune, J K, Grønnesby, E A, Høiby, O, Closs, H, Nøkleby

Publikováno v: NIPH annals. 14(2)

A placebo controlled, double blind efficacy trial with a new outer membrane vesicle vaccine against systemic meningococcal disease of serogroup B, has been conducted in Norwegian secondary schools. The study was randomized at school level (1335 schoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3df9c180cd17d9a8f3db5e4dcc1b51c5
https://pubmed.ncbi.nlm.nih.gov/1812425

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Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway

Autor: J Eng, Ø Arnesen, J.H Fredriksen, L.K Solberg, Hanne Nøkleby, E Holten, L O Frøholm, Høiby Ea, E. Rosenqvist, Alfred Halstensen, L.S Bakketeig, O Closs, A-K Lindbak, Lystad A, B Hareide, Gunnar Bjune, Grønnesby Jk

Publikováno v: Lancet (London, England). 338(8775)

For more than 15 years, Norway has had the highest incidence of meningococcal disease in northern Europe, with 80% of cases being due to serogroup B meningococci. The case-fatality has remained high, at about 10%. In this study, an outer membrane vac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e66079bd5ed00c982af5cd2040ece9
https://pubmed.ncbi.nlm.nih.gov/1683438

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Characterization of Lymphocytes Isolated from Non-lymphoid Human Malignant Tumours

Autor: O. Closs, J.-L. Svennevig, H. Svaar, Morten Harboe

Publikováno v: Scandinavian Journal of Immunology. 7:487-493

Mononuclear cells (MC) were found in suspensions prepared from twenty-one out of twenty-two solid human neoplasms. In three cases it was calculated that more than 1% of the MC could represent contamination by blood MC. Due to technical difficulties a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2d542ad71de7f07e817b84fd132537
https://doi.org/10.1111/j.1365-3083.1978.tb00482.x

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