Zobrazeno 1 - 8
of 8
pro vyhledávání: '"O B Kinstler"'
Publikováno v:
Pharmaceutical Research. 12:1343-1349
Purpose. The objective of this study was to highlight differences in the pulmonary absorption of a monoPEGylated rhG-CSF and rhG-CSF after intratracheal instillation and aerosol delivery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e48dd694c02af00c981f8d3b9408d11
https://doi.org/10.1023/a:1016281925554
https://doi.org/10.1023/a:1016281925554
Publikováno v:
Pharmaceutical research. 13(7)
The liquid stability of rhG-CSF was investigated after polyethylene glycol (PEG) with an average molecular weight of 6000 daltons was covalently attached to the N-terminal methionine residue.The conjugation methods chosen for modifying the N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6bf22302bdb5a0aaaeee5030c3d1eaf
https://pubmed.ncbi.nlm.nih.gov/8842035
https://pubmed.ncbi.nlm.nih.gov/8842035
Autor:
M M, Hokom, D, Lacey, O B, Kinstler, E, Choi, S, Kaufman, J, Faust, C, Rowan, E, Dwyer, J L, Nichol, T, Grasel, J, Wilson, R, Steinbrink, R, Hecht, D, Winters, T, Boone, P, Hunt
Publikováno v:
Blood. 86(12)
Megakaryocyte growth and development factor (MGDF) is a potent inducer of megakaryopoiesis in vitro and thrombopoiesis in vivo. The effects of MGDF appear to be lineage-selective, making this cytokine an ideal candidate for use in alleviating clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::524c65bb567dffe371aa790556ab777e
https://pubmed.ncbi.nlm.nih.gov/8541537
https://pubmed.ncbi.nlm.nih.gov/8541537
Publikováno v:
Pharmaceutical research. 12(9)
The objective of this study was to highlight differences in the pulmonary absorption of a monoPEGylated rhG-CSF and rhG-CSF after intratracheal instillation and aerosol delivery.Male Sprague Dawley rats (250 g) were anesthetized and intratracheally i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bfddd1749fcde7d9f953f9d617b05c0
https://pubmed.ncbi.nlm.nih.gov/8570533
https://pubmed.ncbi.nlm.nih.gov/8570533
Publikováno v:
Chemistry of Natural Compounds. 15:333-337
The covalent binding of L-asparaginase to soluble CM-cellulose has been carried out by the azide method, and some physicochemical properties of the preparation obtained have been studied. It has been established that the modified L-asparaginase posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f6425a246c646ac905aad5bc25adb7
https://doi.org/10.1007/bf00566087
https://doi.org/10.1007/bf00566087
Autor:
L. F. Merengova, I. A. Vina, A. S. Karsakevich, A. P. Kashkin, O. B. Kinstler, N. E. Putilova
Publikováno v:
Chemistry of Natural Compounds. 23:488-492
A precedure has been developed for the chemical binding of L-asparaginase to soluble CM-cellulose which permits final immobilization products with different degrees of modification to be obtained. Some physicochemical and immunological properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f659ff6ec1c74bb7fa59d7918fb87674
https://doi.org/10.1007/bf00597812
https://doi.org/10.1007/bf00597812
Autor:
O B, Kinstler, L V, Kozlov
Publikováno v:
Biokhimiia (Moscow, Russia). 42(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3315588acf14179de8e0b2cd9285407f
https://pubmed.ncbi.nlm.nih.gov/21001
https://pubmed.ncbi.nlm.nih.gov/21001
Publikováno v:
Voprosy meditsinskoi khimii. 34(3)
L-asparaginase, covalently bound with water-soluble CM-cellulose, exhibited the elevated antileukemic activity in mice with inoculated lymphoid leukemia L5178y as compared with the native enzyme. The antileukemic activity of the immobilized enzyme wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16df072336aa21a9e3ed51bdc3151878
https://pubmed.ncbi.nlm.nih.gov/3420797
https://pubmed.ncbi.nlm.nih.gov/3420797