Zobrazeno 1 - 10
of 91
pro vyhledávání: '"O B, Flekhter"'
Autor:
Elena V. Tretyakova, E. I. Boreko, O. B. Flekhter, I. E. Smirnova, Tolstikov Genrikh A, O. V. Savinova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 35:385-390
Synthesis of dihydroquinopymaric acid amides and their 2beta-succinyl and 2beta-phthalyl derivatives containing residues of amino acids was carried out for the first time. Antiviral properties of the compounds synthesized were investigated.
Autor:
O. B. Flekhter, I. V. Glukhov, F. Z. Galin, M. S. Yunusov, N. I. Medvedeva, I. V. Savinova, L. P. Titov, Tolstikov Genrikh A, E. I. Boreko, Huong Nguen Thi Mai, Le Viet Tien
Publikováno v:
Scopus-Elsevier
The rare olean-18(19)-ene triterpenoids moradiol and moronic acid were synthesized from betulin, and their antiviral properties were investigated.
Autor:
O. B. Flekhter, O. V. Savinova, N. I. Medvedeva, F. M. Dolgushin, E. I. Boreko, Tolstikov Genrikh A
Publikováno v:
Russian Journal of Bioorganic Chemistry. 35:118-122
The Beckman rearrangement of carboxy- and alkyloxycarbonylalkylamides of 3-hydroxyiminobetulonic acid led to derivatives of 3a-homo-4-aza-3-oxolup-20(29)-ene and 3,4-seco-2-cyanolupa-4(23),20(29)-diene. An X-ray analysis showed methyl 3-(N-acetoximin
Autor:
Zoya A. Starikova, Alexander A. Korlyukov, Elena V. Tretyakova, I. E. Smirnova, F. Z. Galin, Tolstikov Genrikh A, O. B. Flekhter, Leonid V. Spirikhin
Publikováno v:
Russian Journal of Organic Chemistry. 44:1598-1605
Reduction conditions of methyl dihydroquinopimarate with sodium borohydride and lithium aluminum hydride were established. As a result of the reduction 14β-hydroxy, 17α-hydroxy, 14β,17α-dihydroxy, and 14β,17α,21α-trihydroxy derivatives were ob
Autor:
E. I. Boreko, O. V. Savinova, Leonid V. Spirikhin, E. G. Galkin, Denis G. Golovanov, Kukovinets Olga S, O. B. Flekhter, Tolstikov Genrikh A, N. I. Pavlova, Natalya I. Medvedeva, F. Z. Galin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 33:584-588
A reductive transformation of the peroxide products of ozonolysis of derivatives of 3beta-O-acetyl-22(17-->28)-abeo-lupa-17(28),20(29)-diene and the subsequent intramolecular ketalization led to a compound with a trioxane fragment. This is a new appr
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 182:951-967
In order to search for new anti-tumor and anti-viral agents, a series of α-aminophosphonate conjugates of 3-O-β-acetyl ursolic acid were prepared. Their biological activities as cytotoxic and anti-HIV agents were evaluated. The preliminary bioassay
Publikováno v:
Chemistry of Natural Compounds. 42:706-709
New 2-deoxy-and 2,6-dideoxy-a-L-arabinohexopyranosides of betulinic acid and 28-oxoallobetulin methyl esters were synthesized by the glycal method.
Autor:
Zoya A. Starikova, O. V. Savinova, N. S. Makara, N. I. Pavlova, N. Zh. Baschenko, G. V. Giniyatullina, F. Z. Galin, E. I. Boreko, F. S. Zarudii, Tolstikov Genrikh A, O. B. Flekhter
Publikováno v:
Chemistry of Natural Compounds. 41:706-709
New 20-oxo- and hydroxyimino-derivatives of betulin that exhibit immunotropic and antiviral activities were synthesized.
Autor:
Natalya I. Medvedeva, Baltina Lidiya A, F. S. Zarudii, O. B. Flekhter, Tolstikov Genrikh A, L. T. Karachurina, F. Z. Galin
Publikováno v:
Pharmaceutical Chemistry Journal. 39:401-404
A series of new triterpene hemisuccinates, hemiphthalates and nicotinates have been obtained with 52 – 95% yields via reactions of monoacetates of betulin, betulinic acid, and allobetulin with succinic and phthalic anhydrides and with nicotinic aci
Publikováno v:
Russian Journal of Organic Chemistry. 41:828-831
Diterpenoid 5-hydroxy-1,3-benzoxathiol-2-one and 2-amino-1,3-benzothiazol-6-ol derivatives were synthesized by reaction of methyl chrysenequinonecarboxylate with thiourea.