Zobrazeno 1 - 2
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pro vyhledávání: '"O A Emran"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(8)
Conditional oncogene expression in transgenic mice is of interest for studying the oncoprotein requirements during tumorigenesis and for deriving cell lines that can be induced to undergo growth arrest and enhance their differentiated functions. We u
Autor:
Manju Surana, Gordon C. Weir, David Fusco-Demane, Mark A. Magnuson, Shimon Efrat, Margarita Leiser, Norman Fleischer, T. L. Jetton, Ying-Jian Wu, O A Emran
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(6)
Phosphorylation of glucose to glucose 6-phosphate by glucokinase (GK; EC 2.7.1.2) serves as a glucose-sensing mechanism for regulating insulin secretion in beta cells. Recent findings of heterozygous GK gene mutations in patients with maturity-onset