Výsledky vyhledávání - "O A, Lapchinskaia"

[Streptonigron--a minor component of bruneomycin complex]

Autor: N V, Kozlova, N A, L'vova, O A, Lapchinskaia, E B, Dokuchaeva, L M, Rubasheva, B V, Rozynov, M N, Preobrazhenskaia

Publikováno v: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 35(5)

A mutant strain of the bruneomycin-producing culture which produced up to 10% of the minor component was selected. The component was identified as streptonigrone. It was isolated and its physicochemical properties and antibacterial activity were inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b36b4adbc6e225879433ddbe883be4b7
https://pubmed.ncbi.nlm.nih.gov/2116780

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[Obtaining a productive strain of Streptoverticillium griseocarneum var. bleomycini that yields the new antineoplastic antibiotic, bleomycetin]

Autor: V V, Pogozheva, O A, Lapchinskaia, O P, Siniagina, L S, Pokras

Publikováno v: Antibiotiki. 25(12)

Selection of the organism producing bleomycin, a multicomponent antitumor antibiotic, was performed. The aim was the selection of a more active strain with preferable synthesis of component A5 (bleomycetin) of the bleomycin complex. Optimal variants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53eed15dd6275f0081524902762f431b
https://pubmed.ncbi.nlm.nih.gov/6162418

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[Selection of the productive variants in a culture of Streptomyces olivoreticuli 16749, the producer of olivomycin]

Autor: N A, L'vova, O A, Lapchinskaia

Publikováno v: Antibiotiki. 26(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52dfa60f69cdb1487fd17cba8dab1e53
https://pubmed.ncbi.nlm.nih.gov/7325620

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[Use of auxotrophic mutations in selection of a producer of the antitumor antibiotic carminomycin]

Autor: O A, Lapchinskaia, T P, Saburova, V I, Ponomarenko

Publikováno v: Antibiotiki. 19(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::103f1976eb9ce7b05d873668e47d0a6e
https://pubmed.ncbi.nlm.nih.gov/4463870

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[Selection of active strains of Actinomadura carminata, the producer of carminomycin]

Autor: V A, Filicheva, O A, Lapchinskaia, T P, Saburova, O P, Siniagina, V I, Ponomarenko

Publikováno v: Antibiotiki. 23(1)

The method of selecting active strains among a definite group of analogue-resistant mutants was used on the basis of studying the dependence of the carminomycin-producing organism growth and the antibiotic synthesis level on some metabolites. As a re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ddfa14180a6f0c57ae2ef64953f857b
https://pubmed.ncbi.nlm.nih.gov/623444

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[Obtaining mutants that yield tobramycin in a culture of the producer of a complex of aminoglycoside antibiotics, Streptomyces cremeus var. tobramycini var. nov. 2242]

Autor: O P, Siniagina, O A, Lapchinskaia, M F, Lavrova-Balashova, T P, Nesterova, V I, Ponomarenko

Publikováno v: Antibiotiki. 25(12)

The organism producing an aminoglycoside antibiotic complex was subjected to selection with a purpose of obtaining a strain producing tobramycin. Spontaneous and gamma-radiation-induced variation of the strains obtained as a result of a step-wise sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a7da06462b18a14fabecb2aa664e8df
https://pubmed.ncbi.nlm.nih.gov/7469392

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[Action of acridine dyes on antibiotic, pigment and aerial mycelium formation in streptomycete producers of multicomponent antibiotics]

Autor: O A, Lapchinskaia, N A, L'vova, O P, Siniagina, V V, Pogozheva, V A, Filicheva

Publikováno v: Antibiotiki. 26(11)

The ability of 5 streptomycetous species synthesizing multicomponent antibiotic to produce the antibiotic and water-soluble pigment and to form the aerial mycelium in the presence of acridine dyes was studied. It was found that the character of the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afdb7eba067eb53875ac057d1d790c1a
https://pubmed.ncbi.nlm.nih.gov/7325614

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[Effect of antibiotic resistance on the appearance of mutants in a culture of Streptomyces cremeus subsp. tobramycini producing an aminoglycoside complex]

Autor: O P, Siniagina, O A, Lapchinskaia

Publikováno v: Antibiotiki. 28(4)

Possible formation of auxotrophs and changing of the antibiotic production property connected with resistance to antibiotics of different modes of action were studied in Streptomyces cremeus subsp. tobramycini producing the nebramycin complex of 2-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b84fa361678bf96e385ffd60db6ca4b3
https://pubmed.ncbi.nlm.nih.gov/6859825

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[Production of active mutants of a new species of rifamycin producer resistant to specific actinophage]

Autor: O A, Lapchinskaia, V V, Zhunaeva, V V, Pogozheva, E M, Trutneva, V A, Filicheva

Publikováno v: Antibiotiki. 20(5)

Selection of a phage-stable strain of a new species of the rifamycin-producing organism was carried out. The phage-stable mutants were selected with respect to the virulent phage 2739 isolated from a lysogenic culture of the rifamycin-producing organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfca2e90ae522a03b4de8a9cd765a5a3
https://pubmed.ncbi.nlm.nih.gov/1225186

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