Zobrazeno 1 - 10
of 3 490
pro vyhledávání: '"O‐GlcNAcylation"'
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Developing resistance to cancer treatments is a major challenge, often leading to disease recurrence and metastasis. Understanding the underlying mechanisms of therapeutic resistance is critical for developing effective strategies. O-GlcNAcy
Externí odkaz:
https://doaj.org/article/72fc510600394a2cb0ee3cd1f4cf80bb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Peritoneal fibrosis has been linked to hypoxia-inducible factor 1-alpha (HIF-1α) as well as O-linked-N-acetylglucosaminylation (O-GlcNAcylation) in peritoneal dialysis (PD). Genistein, recognized for its HIF-1α inhibitory and antifibrotic
Externí odkaz:
https://doaj.org/article/20e5856c3e5646b18d005437d5946abc
Autor:
Yu Du, Xiang Gao, Jianqiang Chen, Xinxin Chen, Hang Liu, Wenge He, Lu Liu, Yue Jiang, Baicheng He, Zhongliang Deng, Chao Liang, Fengjin Guo
Publikováno v:
Journal of Orthopaedic Translation, Vol 50, Iss , Pp 14-29 (2025)
Background: O-GlcNAc transferase (OGT) is responsible for attaching O-linked N-acetylglucosamine (O-GlcNAc) to proteins, regulating diverse cellular processes ranging from transcription and translation to signaling and metabolism. This study focuses
Externí odkaz:
https://doaj.org/article/819e7114b22e4e3ab22ad13a1f717b5c
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a common and important post-translational modification (PTM) linking O-linked β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues in proteins. Extensive research indicate
Externí odkaz:
https://doaj.org/article/5a6908ab985f4c6aafbf3b7b00cec22c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Myocardial ischemia-reperfusion injury (MIRI) is a significant complication following reperfusion therapy after myocardial infarction. Mitochondrial oxidative stress is a critical factor in MIRI, and Sirtuin 3 (SIRT3), as a major mitochondri
Externí odkaz:
https://doaj.org/article/aec63f5bf9f248e79ebe2aab73bd0c90
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract O-linked N-acetylglucosamine protein modification (O-GlcNAcylation) is a dynamic post-translational modification (PTM) involving the covalent binding of serine and/or threonine residues, which regulates bone cell homeostasis. Reactive oxygen
Externí odkaz:
https://doaj.org/article/8a6a4b92f88b483ca835b970bdd78b79
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
O-GlcNAcylation is a dynamic post-translational modification involving the attachment of N-acetylglucosamine to serine and threonine residues. This review emphasizes its role in regulating the signaling pathways of pyroptosis. Specifically, the O-Glc
Externí odkaz:
https://doaj.org/article/9578e97b8c774445ab68293605554963
Autor:
Xingxian Guo, Fan Yang, Tianyi Liu, Amei Chen, Dina Liu, Jiangxia Pu, Can Jia, Yuanhong Wu, Junfeng Yuan, Nan Ouyang, Joachim Herz, Yinyuan Ding
Publikováno v:
Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)
Abstract Low‐density lipoprotein receptor‐related protein‐1 (LRP1) is thought to be correlated with hepatocellular carcinoma (HCC) invasion and metastasis. However, the precise mechanism through which LRP1 contributes to HCC progression remains
Externí odkaz:
https://doaj.org/article/234da93c530e41e1b49bbf38c71a411e
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Backgrounds The role of O-GlcNAc transferase (OGT)-induced O-linked N-acetylglucosaminylation (O-GlcNAcylation) has been reported in multiple human diseases. However, its specific functions in osteoarthritis (OA) progression remain undetermined.Objec
Externí odkaz:
https://doaj.org/article/11f35befe564428e9fd408f6dc153f53