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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies

Autor: Altincekic, Nadide, Jores, Nathalie, Löhr, Frank, Richter, Christian, Ehrhardt, Claus, Blommers, Marcel J. J., Berg, Hannes, Öztürk, Sare, Gande, Santosh L., Linhard, Verena, Orts, Julien, Abi Saad, Marie Jose, Bütikofer, Matthias, Kaderli, Janina, Karlsson, B. Göran, Brath, Ulrika, Hedenström, Mattias, Gröbner, Gerhard, Sauer, Uwe H., Perrakis, Anastassis, Langer, Julian, Banci, Lucia, Cantini, Francesca, Fragai, Marco, Grifagni, Deborah, Barthel, Tatjana, Wollenhaupt, Jan, Weiss, Manfred S., Robertson, Angus, Bax, Adriaan, Sreeramulu, Sridhar, Schwalbe, Harald

Publikováno v: ACS Chemical Biology; February 2024, Vol. 19 Issue: 2 p563-574, 12p

Yırca'da kadın olmak ve köylü kadın emeği: Bir güçlenme deneyimi olarak Yırcalı kadınlar

Autor: Öztürk, Sare

Bu çalışma, Manisa'nın Soma ilçesine bağlı Yırca Köyü'ndeki kadınların emeği ve mücadele deneyimini konu almaktadır. Feminist metodoloji ve etnografik yöntemle yapılan araştırma, derinlemesine görüşme ve katılımlı gözlemle e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10208::f71687c3cfc3dca832307d5931762863
https://acikbilim.yok.gov.tr/handle/20.500.12812/624157

Targeting the Main Protease (M ^pro , nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Autor: Altincekic N; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Jores N; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Löhr F; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Institute of Biophysical Chemistry, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Richter C; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Ehrhardt C; Department of Biochemistry, University of Zurich, 8093 Zurich, Switzerland., Blommers MJJ; SavernaTherapeutics, 4105 Biel-Benken, Switzerland., Berg H; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Öztürk S; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Gande SL; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Linhard V; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Orts J; Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria., Abi Saad MJ; Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria., Bütikofer M; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, 8093 Zürich, Switzerland., Kaderli J; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, 8093 Zürich, Switzerland., Karlsson BG; Swedish NMR Centre, Department of Chemistry and Molecular Biology, University of Gothenburg, SE40530 Göteborg, Sweden.; SciLifeLab, University of Gothenburg, SE40530 Göteborg, Sweden., Brath U; Swedish NMR Centre, Department of Chemistry and Molecular Biology, University of Gothenburg, SE40530 Göteborg, Sweden., Hedenström M; Swedish NMR Centre, Department of Chemistry, University of Umeå, SE-90187 Umeå, Sweden., Gröbner G; Swedish NMR Centre, Department of Chemistry, University of Umeå, SE-90187 Umeå, Sweden., Sauer UH; Protein Production Sweden, Department of Chemistry, University of Umeå, SE-90187 Umeå, Sweden., Perrakis A; Oncode Institute and Division of Biochemistry, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Langer J; Max Planck Institute of Biophysics, D-60438 Frankfurt am Main, Germany., Banci L; Magnetic Resonance Center and Department of Chemistry, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy.; Consorzio Interuniversitario Risonanze Magnetiche Metalloproteine, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy., Cantini F; Magnetic Resonance Center and Department of Chemistry, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy.; Consorzio Interuniversitario Risonanze Magnetiche Metalloproteine, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy., Fragai M; Magnetic Resonance Center and Department of Chemistry, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy.; Consorzio Interuniversitario Risonanze Magnetiche Metalloproteine, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy., Grifagni D; Magnetic Resonance Center and Department of Chemistry, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy., Barthel T; Macromolecular Crystallography, Helmholtz-Zentrum Berlin, Albert-Einstein-Str. 15, D-12489 Berlin, Germany., Wollenhaupt J; Macromolecular Crystallography, Helmholtz-Zentrum Berlin, Albert-Einstein-Str. 15, D-12489 Berlin, Germany., Weiss MS; Macromolecular Crystallography, Helmholtz-Zentrum Berlin, Albert-Einstein-Str. 15, D-12489 Berlin, Germany., Robertson A; NIH, LCP NIDDK, Bethesda, Maryland 20892, United States., Bax A; NIH, LCP NIDDK, Bethesda, Maryland 20892, United States., Sreeramulu S; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany., Schwalbe H; Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.; Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am Main, D-60438 Frankfurt, Germany.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2024 Feb 16; Vol. 19 (2), pp. 563-574. Date of Electronic Publication: 2024 Jan 17.