Zobrazeno 1 - 10
of 223
pro vyhledávání: '"O, Westergaard"'
Autor:
Estifanos N. Habtemichael, Chloe I. Sales, Francesc López-Giráldez, Xavier O. Westergaard, Hanbing Li, Jonathan S. Bogan, Pamela Dann, Stephen G. DeVries, Don T. Li, Joao Paulo Camporez, Gerald I. Shulman, Stacey N. Brown, Sandro M. Hirabara, William M. Philbrick, Diana M. Ruiz, Xinran Liu, Bhavesh S. Sayal, Sofia González Zapata, Daniel F. Vatner, Kenny Y. Wang, Leigh Goedeke
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature metabolism
Universidade de São Paulo (USP)
instacron:USP
Nature metabolism
TUG tethering proteins bind and sequester GLUT4 glucose transporters intracellularly, and insulin stimulates TUG cleavage to translocate GLUT4 to the cell surface and increase glucose uptake. This effect of insulin is independent of phosphatidylinosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee128277fb5c4809393ded802df5555
Autor:
Estifanos N. Habtemichael, Diana M. Ruiz, Daming Li, Bhavesh S. Sayal, Camporez Jp, Wang Ky, Henry Li, Sandro M. Hirabara, Xinran Liu, Daniel F. Vatner, Chloe I. Sales, Stephen G. DeVries, Gerald I. Shulman, William M. Philbrick, Francesc López-Giráldez, Xavier O. Westergaard, Jonathan S. Bogan
SummaryMechanisms to coordinately regulate energy expenditure and glucose uptake into muscle and fat cells are not well described. Insulin stimulates glucose uptake in part by causing site-specific endoproteolytic cleavage of TUG, which mobilizes GLU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa879116ceb2fc779c015883b7fe8779
https://doi.org/10.1101/817049
https://doi.org/10.1101/817049
Autor:
Don T, Li, Estifanos N, Habtemichael, Omar, Julca, Chloe I, Sales, Xavier O, Westergaard, Stephen G, DeVries, Diana, Ruiz, Bhavesh, Sayal, Jonathan S, Bogan
Publikováno v:
The Yale Journal of Biology and Medicine
Fat and muscle cells contain a specialized, intracellular organelle known as the GLUT4 storage vesicle (GSV). Insulin stimulation mobilizes GSVs, so that these vesicles fuse at the cell surface and insert GLUT4 glucose transporters into the plasma me
Autor:
Estifanos N. Habtemichael, Xavier O. Westergaard, Joseph S. Wolenski, Eric Li, Jonathan S. Bogan, Hanbing Li, Stephen G. DeVries, Abel R. Alcázar-Román, Don T. Li, Max C. Petersen, Muyi Li, Omar Julca-Zevallos
Insulin stimulates the exocytic translocation of specialized vesicles in adipocytes, which inserts GLUT4 glucose transporters into the plasma membrane to enhance glucose uptake. Previous results support a model in which TUG (Tether containing a UBX d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482d807d8be49ac1253f76526500e324
https://europepmc.org/articles/PMC6036200/
https://europepmc.org/articles/PMC6036200/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 94
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 95
Publikováno v:
Molecular biology reports. 27(1)
The Rad52 protein plays a crucial role in repairing DNA damage and homologous recombination, possibly by virtue of its ability to catalyze annealing of single-stranded DNA. In agreement with recent genetic data, we here present results based on the t
Autor:
Flemming Besenbacher, O. Westergaard, Erik Lægsgaard, Ivan Stensgaard, C. Bendixen, B. Thomsen
Publikováno v:
Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 8:703-705
The capability of the scanning tunneling microscope (STM) to produce atomic‐resolution images makes it a powerful tool in both basic and applied science. The main application of STM has been for the analysis of structural features and electronic pr
Publikováno v:
Biochemistry. 37(47)
In mammalian cells, DNA topoisomerase II is the product of two distinct genes encoding the alpha and beta isoforms of the enzyme. Besides homodimeric topoisomerase IIalpha and IIbeta, we have recently shown that alpha/beta heterodimers constitute a t
Publikováno v:
The Journal of biological chemistry. 273(34)
The strand joining step of recombination mediated by the Flp site-specific recombinase involves the attack of a 3'-phosphotyrosyl bond by a 5'-hydroxyl group from DNA. The nucleophile in this reaction, the 5'-OH, can be substituted by glycerol or oth