Výsledky vyhledávání - "O, Varoquaux"

Evaluation of the alpha 2-adrenoceptor blocking properties of buspirone and ipsapirone in healthy subjects. Relationship with the plasma concentration of the common metabolite 1-(2-pyrimidinyl)-piperazine

Autor: G Schollnhammer, F Cesselin, O Varoquaux, C. Payan, Stephan Chalon, Alain J. Puech, Ivan Berlin

Publikováno v: British Journal of Clinical Pharmacology. 39:243-249

1. Because the 5-HT1A agonist anxiolytic azapirones have a common alpha 2-adrenoceptor antagonist metabolite, 1-(2-pyrimidinyl)-piperazine (1PP), we measured central and peripheral alpha 2-adrenoceptor dependent responses before and after intravenous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e99914e78371f5c3dc418814d2297f
https://doi.org/10.1111/j.1365-2125.1995.tb04443.x

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Compared plasma and brain pharmacokinetics of clomipramine and its metabolite demethylclomipramine in two strains of mice (NMRI and CD1)

Autor: Alain Eschalier, E. Duroux, Charles Advenier, P. Cordonnier, C. Bulach, O. Varoquaux, M. Pays, H. Marty, J. Fialip, P. Bastide

Publikováno v: Fundamental & Clinical Pharmacology. 6:49-57

The fate of clomipramine (CMI) and its main demethylated metabolite demethylclomipramine (DCMI) was studied in two strains of Swiss mice (NMRI and CD1) after intraperitoneal injection. A study of its distribution among various tissues showed that fix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f882a345cde3495161e272be2c3448d
https://doi.org/10.1111/j.1472-8206.1992.tb00094.x

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Quinidine oxidative metabolism. Identification and biosynthesis of quinidine 10,11-dihydrodiol stereoisomers

Autor: R. Leroyer, O. Varoquaux, M. Pays, Charles Advenier

Publikováno v: Biomedical Chromatography. 4:61-64

The isocratic reversed phase high performance liquid chromatographic method proposed for quinidine metabolic studies facilitates particularly the separation of 10(R) and (S) isomers of quinidine 10,11-dihydrodiols. The finding of each of these forms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b72d511fc928918f9a5675ad38c253
https://doi.org/10.1002/bmc.1130040205

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[Diffusion of minocycline in pulmonary tissue]

Autor: E, Naline, J P, Roudière, P, Cordonnier, O, Varoquaux, N, Brion, L, Toty, H, Bakdach, M, Pays, C, Advenier

Publikováno v: Therapie. 46(1)

The penetration of minocycline into lung tissue was evaluated in 14 patients about to undergo excision of the lung for cancer. The patients received minocycline orally in doses of 100 mg twice a day for 3 days, the 100 mg in the morning of the operat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a53ef5aae50e142137fc289c9524121
https://pubmed.ncbi.nlm.nih.gov/1850557

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