Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics

Autor: Jelmer Raaijmakers, Budi O. Susanto, Heiman F. L. Wertheim, Erik van den Hombergh, Mike Marvin Ruth, Ulrika S. H. Simonsson, Wouter Hoefsloot, Jakko van Ingen, Elin M. Svensson, Rob E. Aarnoutse

Publikováno v: Clinical Microbiology and Infection, 28, 448.e1-448.e7
Clinical Microbiology and Infection, 28, 3, pp. 448.e1-448.e7

Contains fulltext : 248659.pdf (Publisher’s version ) (Open Access) OBJECTIVES: Mycobacterium avium complex (MAC) bacteria can cause chronic pulmonary disease (PD). Current treatment regimens of azithromycin, ethambutol and rifampicin have culture

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd34ba04db8b657b88ac438c7abaeae2
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-481678

Rifampicin Can Be Given as Flat-Dosing Instead of Weight-Band Dosing

Autor: Rob E. Aarnoutse, Martin J. Boeree, Elin M. Svensson, Robin J. Svensson, Ulrika S. H. Simonsson, Budi O. Susanto

Publikováno v: Clinical Infectious Diseases, 71, 3055-3060
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 71, 12, pp. 3055-3060

Background The weight-band dosing in tuberculosis treatment regimen has been implemented in clinical practice for decades. Patients will receive different number of fixed dose combination tablets according to their weight-band. However, some analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f764285a74981923263f88065b778f
http://hdl.handle.net/2066/230624

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Controversies in granzyme biology

Autor: O, Susanto, J A, Trapani, D, Brasacchio

Publikováno v: Tissue antigens. 80(6)

Granzymes (Grz) are a family of serine proteases found in the granules of cytotoxic lymphocytes and are emerging as an important group of proteins involved in immune function and surveillance. Grz have both cytotoxic and more recently reported non-cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c2bf103d01f596849f1fdeabef45c13
https://pubmed.ncbi.nlm.nih.gov/23137319

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.