Zobrazeno 1 - 10 of 54 pro vyhledávání: '"O, Kopyov"'
1
Akademický článek
Transplantation of Human Neural Progenitor Cells (NPC) into Putamina of Parkinsonian Patients: A Case Series Study, Safety and Efficacy Four Years after Surgery
Autor: I. Madrazo, O. Kopyov, M. A. Ávila-Rodríguez, F. Ostrosky, H. Carrasco, A. Kopyov, A. Avendaño-Estrada, F. Jiménez, E. Magallón, C. Zamorano, G. González, T. Valenzuela, R. Carrillo, F. Palma, R. Rivera, R. E. Franco-Bourland, G. Guízar-Sahagún
Publikováno v: Cell Transplantation, Vol 28 (2019)
Individuals with Parkinson’s disease (PD) suffer from motor and mental disturbances due to degeneration of dopaminergic and non-dopaminergic neuronal systems. Although they provide temporary symptom relief, current treatments fail to control motor
Externí odkaz: https://doaj.org/article/8cdd4a35d2dc46d29f285bb8ced1eeb3
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2
Akademický článek
Efficacy of Two Delivery Routes for Transplanting Human Neural Progenitor Cells (NPCs) into the Spastic Han–Wistar Rat, a Model of Ataxia
Autor: Toni L. Uhlendorf, Ruslan L. Nuryyev, Alex O. Kopyov, Jessica Ochoa, Shahab Younesi, Randy W. Cohen, Oleg V. Kopyov
Publikováno v: Cell Transplantation, Vol 26 (2017)
An emerging avenue for recalcitrant neurodegenerative disease treatment is neural progenitor cell (NPC) transplantation. In this study, we investigated the effectiveness of two different delivery routes of human-derived NPC inoculation: injection int
Externí odkaz: https://doaj.org/article/e7b0417e0504429a8987b144120e78d4
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4
Transplantation of Human Neural Progenitor Cells (NPC) into Putamina of Parkinsonian Patients: A Case Series Study, Safety and Efficacy Four Years after Surgery
Autor: Miguel A. Avila-Rodriguez, F. Ostrosky, Gabriel Guízar-Sahagún, T. Valenzuela, O. Kopyov, A. Kopyov, H. Carrasco, Carlos Zamorano, A. Avendaño-Estrada, I. Madrazo, R. Carrillo, R. Rivera, G. González, F. Jiménez, Eduardo Magallon, R. E. Franco-Bourland, F. Palma
Publikováno v: Cell Transplantation, Vol 28 (2019)
Cell Transplantation
Individuals with Parkinson’s disease (PD) suffer from motor and mental disturbances due to degeneration of dopaminergic and non-dopaminergic neuronal systems. Although they provide temporary symptom relief, current treatments fail to control motor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d613a639724b52308d9a03d325d2a4c
https://doaj.org/article/8cdd4a35d2dc46d29f285bb8ced1eeb3
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5
Entopeduncular lesions facilitate and thalamic lesions depress spontaneous and drug-evoked motor behavior in the hemiparkinsonian rat
Autor: O. Kopyov, D.B. Jacques, M.E. Olds
Publikováno v: Synapse. 40:215-224
Pallidotomy is a neurosurgical procedure designed to ameliorate the akinesia and bradykinesia associated with Parkinson's disease. In the present study, the effects of pallidal-like lesions on motor behavior in the hemiparkinsonian rat were compared
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5545fa2d7ca5086ad75249779d286d
https://doi.org/10.1002/syn.1044
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6
Subthalamic responses to amphetamine and apomorphine in the behaving rat with a unilateral 6-OHDA lesion in the substantia nigra
Autor: M.E. Olds, O. Kopyov, D.B. Jacques
Publikováno v: Synapse. 34:228-240
The activity of neurons in the subthalamic nucleus (STN) of the behaving rat, before and after a unilateral 6-OHDA lesion of the substantia nigra, was recorded with the extracellular technique to determine whether it was altered following systemic am
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5f96bd69697e1d7777a82ba0978ee2d
https://doi.org/10.1002/(sici)1098-2396(19991201)34:3<228::aid-syn7>3.0.co
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7
Relation between rotation in the 6-OHDA lesioned rat and dopamine loss in striatal and substantia nigra subregions
Autor: O. Kopyov, M.E. Olds, D.B. Jacques
Publikováno v: Synapse (New York, N.Y.). 59(8)
The relation between the rotation response to drug-induced activation of the dopamine (DA) receptor in the rat unilaterally lesioned with 6-hydroxydopamine (6-OHDA) in the substantia nigra (SN) and the loss of DA in subregions of the SN and caudate-p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b55df4b9a67c8a02393d8eb0fef66a
https://pubmed.ncbi.nlm.nih.gov/16565974
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8
Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat
Autor: D.B. Jacques, O. Kopyov, M.E. Olds
Publikováno v: Synapse (New York, N.Y.). 55(1)
Parkinson's disease (PD), a hypokinetic disorder, and Huntington's disease (HD), a hyperkinetic disorder, share the fact that in the motor pathways the dysfunction starts in the striatum. In PD the projection neurons are overactive due to decreased i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a4e219f848ee8d586c3e61f5623fe3
https://pubmed.ncbi.nlm.nih.gov/15499610
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9
Behavioral and subthalamic effects of combining a fetal ventral mesencephalic transplant in striatum with an electrolytic lesion of the entopeduncular nucleus in the rat with a unilateral 6-OHDA lesion of substantia nigra
Autor: M.E. Olds, O. Kopyov, D.B. Jacques
Publikováno v: Synapse (New York, N.Y.). 48(2)
Behavioral and electrophysiological methods were used to determine whether a transplant of dopamine-rich fetal tissue in striatum combined with an electrolytic lesion of the entopeduncular nucleus have additive effects in the unilaterally lesioned ra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd1299200292ef3e263d3855c350eac
https://pubmed.ncbi.nlm.nih.gov/12619043
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