Zobrazeno 1 - 10
of 52
pro vyhledávání: '"O'neil W, Guthrie"'
Autor:
O'neil W. Guthrie, Ishan S. Bhatt
Publikováno v:
Biology Open, Vol 10, Iss 10 (2021)
Over 1.1 billion individuals are at risk for noise induced hearing loss yet there is no accepted therapy. A long history of research has demonstrated that excessive noise exposure will kill outer hair cells (OHCs). Such observations have fueled the n
Externí odkaz:
https://doaj.org/article/5ecf47b1545c4c20b9ffdd71440fd5a7
Publikováno v:
Journal of Cancer Survivorship. 17:17-26
Autor:
O'Neil W, Guthrie
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 85:671-684
A fundamental property of first-order sensory neurons is the ability to alter their response properties as a function of change in the statistical parameters of an input signal. Such neural adaptation shapes the performance features of contiguous neu
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 85:175-183
Degenerate neural circuits exhibit "different" circuit properties yet produce similar circuit outcomes (many-to-one) which ensures circuit robustness and complexity. However, neuropathies may hijack degeneracy to yield robust and complex pathological
Autor:
Ali Torkamani, Sheila R. Pratt, O'neil W. Guthrie, Jin Wang, Jason A. Wilder, Nathan E. Wineinger, Ishan Sunilkumar Bhatt, Raquel Dias, Nilesh J Washnik
Publikováno v:
Ear Hear
OBJECTIVES About 15% of U.S. adults report speech perception difficulties despite showing normal audiograms. Recent research suggests that genetic factors might influence the phenotypic spectrum of speech perception difficulties. The primary objectiv
Autor:
O’neil W. Guthrie, Brian A. Wong, Shawn M. McInturf, James E. Reboulet, Pedro A. Ortiz, David R. Mattie
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Occupational exposure to complex blends of organic solvents is believed to alter brain functions among workers. However, work environments that contain organic solvents are also polluted with background noise which raises the issue of whether or not
Externí odkaz:
https://doaj.org/article/b0f6447fcced4dfbb81482afa13c419e
Publikováno v:
Journal of Comparative Physiology A. 205:481-489
Acoustic communication is a fundamental component of mate and competitor recognition in a variety of taxa and requires animals to detect and differentiate among acoustic stimuli (Bradbury and Vehrencamp in Principles of animal communication, 2nd edn.
Publikováno v:
Hearing research. 404
Age-related and noise-induced hearing loss disorders are among the most common pathologies affecting Americans across their lifespans. Loss of auditory feedback due to hearing disorders is correlated with changes in voice and speech-motor control in
Publikováno v:
The Journal of the Acoustical Society of America. 149:A78-A78
Autor:
O'neil W. Guthrie
Publikováno v:
The Anatomical Record. 300:520-526
An understanding of the molecular pathology that underlies noise induced neurotoxicity is a prerequisite to the design of targeted therapies. The objective of the current experiment was to determine whether or not DNA damage is part of the pathophysi