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Spatiotemporal modulation of growth factors directs the generation of multilineage mouse embryonic stem cell-derived mammary organoids.

Autor: Sahu S; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Sahoo S; Department of Bioengineering, Indian Institute of Science, Bengaluru 560012, India., Sullivan T; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., O'Sullivan TN; Centre for Advanced Preclinical Research (CAPR), National Cancer Institute, Frederick, MD 21702, USA., Turan S; Leidos Biomedical Sciences, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Albaugh ME; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA; Leidos Biomedical Sciences, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Burkett S; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Tran B; Leidos Biomedical Sciences, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Salomon DS; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Kozlov SV; Centre for Advanced Preclinical Research (CAPR), National Cancer Institute, Frederick, MD 21702, USA; Leidos Biomedical Sciences, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA., Koehler KR; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA; Department of Otolaryngology, Department of Plastic & Oral Surgery, and the F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA., Jolly MK; Department of Bioengineering, Indian Institute of Science, Bengaluru 560012, India., Sharan SK; Mouse Cancer Genetics Program (MCGP), Centre for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA; Centre for Advanced Preclinical Research (CAPR), National Cancer Institute, Frederick, MD 21702, USA. Electronic address: sharans@mail.nih.gov.

Publikováno v: Developmental cell [Dev Cell] 2024 Jan 22; Vol. 59 (2), pp. 175-186.e8. Date of Electronic Publication: 2023 Dec 29.

Novel Humanized Mesothelin-Expressing Genetically Engineered Mouse Models Underscore Challenges in Delivery of Complex Therapeutics to Pancreatic Cancers.

Autor: Hagerty B; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.; Surgical Oncology Program, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., O'Sullivan TN; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Zhang X; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Collins NK; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Custer Lawrence W; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Bassel LL; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Pate N; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Xu J; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Guerin TM; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland., Kozlov S; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, Maryland. alewinecc@mail.nih.gov christine.alewine@nih.gov kozlovse@nci.gov., Alewine C; Laboratory of Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland. alewinecc@mail.nih.gov christine.alewine@nih.gov kozlovse@nci.gov.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Oct; Vol. 20 (10), pp. 2082-2092. Date of Electronic Publication: 2021 Jul 26.

Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues.

Autor: Song Y; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America., Gilbert D, O'Sullivan TN, Yang C, Pan W, Fathalizadeh A, Lu L, Haines DC, Martin PL, Van Dyke T

Publikováno v: PloS one [PLoS One] 2013 Dec 02; Vol. 8 (12), pp. e80459. Date of Electronic Publication: 2013 Dec 02 (Print Publication: 2013).