Interactions of the male contraceptive target EPPIN with semenogelin-1 and small organic ligands.

Autor: Gomes AAS; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil. antonielaugusto@gmail.com.; Laboratory of Biological Physics, Carlos Chagas Filho Institute of Biophysics, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. antonielaugusto@gmail.com., Santos NCM; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil., Rosa LR; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil., Borges RJ; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil.; The Center of Medicinal Chemistry (CQMED), Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas (UNICAMP), Campinas, Brazil., Fontes MRM; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil.; Institute for Advanced Studies of the Sea (IEAMAR), São Paulo State University, UNESP, São Vicente, SP, Brazil., Hamil KG; Research and Development, Eppin Pharma Inc., Chapel Hill, NC, USA., O'Rand MG; Research and Development, Eppin Pharma Inc., Chapel Hill, NC, USA.; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Silva EJR; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, São Paulo State University, Botucatu, SP, Brazil. ejr.silva@unesp.br.

Publikováno v: Scientific reports [Sci Rep] 2023 Sep 01; Vol. 13 (1), pp. 14382. Date of Electronic Publication: 2023 Sep 01.

Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines.

Autor: Wang C; Division of Endocrinology, Department of Medicine and Clinical and Translational Science Institute, The Lundquist Insitute and Harbor-UCLA Medical Center, Torrance, California, USA., Meriggiola MC; Division of Gynecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Amory JK; Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA., Barratt CLR; Division of Systems and Cellular Medicine, Medical School, Ninewells Hospital, University of Dundee, Dundee, Scotland., Behre HM; Center for Reproductive Medicine and Andrology, University Medicine Halle, Halle, Germany., Bremner WJ; Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA., Ferlin A; Unit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italy., Honig S; Division of Reproductive and Sexual Medicine, Department of Urology, Yale University School of Medicine, New Haven, Connecticut, USA., Kopa Z; Department of Urology, Andrology Centre, Semmelweis University, Budapest, Hungary., Lo K; Division of Urology, Department of Surgery, University of Toronto, Toronto, Canada., Nieschlag E; Center of Reproductive Medicine and Andrology, University Hospital, Münster, Germany., Page ST; Division of Metabolism, Endocrinology and Nutrition, UW Medicine Diabetes Institute, University of Washington School of Medicine, Seattle, Washington, USA., Sandlow J; Department of Urology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Sitruk-Ware R; Center for Biomedical Research, Population Council, New York, New York, USA., Swerdloff RS; Division of Endocrinology, Department of Medicine, The Lundquist Institute and Harbor-UCLA Medical Center, Torrance, California, USA., Wu FCW; Division of Endocrinology, Diabetes and Gastroenterology, Faculty of Biology, Medicine and Health, School of Medical Sciences, University of Manchester, Manchester, UK., Goulis DG; First Department of Obstetrics and Gynecology, Unit of Reproductive Endocrinology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Publikováno v: Andrology [Andrology] 2024 Oct; Vol. 12 (7), pp. 1470-1500. Date of Electronic Publication: 2023 Sep 20.

Inhibition of sperm motility in male macaques with EP055, a potential non-hormonal male contraceptive.

Autor: O'Rand MG; Department of Cell Biology & Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Research and Development, Eppin Pharma Inc., Chapel Hill, North Carolina, United States of America., Hamil KG; Research and Development, Eppin Pharma Inc., Chapel Hill, North Carolina, United States of America., Adevai T; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Zelinski M; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.; Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, United States of America.

Publikováno v: PloS one [PLoS One] 2018 Apr 19; Vol. 13 (4), pp. e0195953. Date of Electronic Publication: 2018 Apr 19 (Print Publication: 2018).

Distinct actions of testicular endocrine and lumicrine signaling on the proximal epididymal transcriptome.

Autor: Kiyozumi, Daiji^1,2,3 (AUTHOR) kiyozumi.daiji.m6@f.mail.nagoya-u.ac.jp

Publikováno v: Reproductive Biology & Endocrinology. 4/10/2024, Vol. 22 Issue 1, p1-15. 15p.

Sperm Toolbox—A selection of small molecules to study human spermatozoa.

Autor: Gruber, Franz S.¹ (AUTHOR), Richardson, Anthony² (AUTHOR), Johnston, Zoe C.³ (AUTHOR), Myles, Rachel³ (AUTHOR), Norcross, Neil R.² (AUTHOR), Day, David P.² (AUTHOR), Georgiou, Irene² (AUTHOR), Sesma-Sanz, Laura¹ (AUTHOR), Wilson, Caroline² (AUTHOR), Read, Kevin D.² (AUTHOR), Martins da Silva, Sarah² (AUTHOR), Barratt, Christopher L. R.³ (AUTHOR), Gilbert, Ian H.² (AUTHOR), Swedlow, Jason R.¹ (AUTHOR) jrswedlow@dundee.ac.uk

Publikováno v: PLoS ONE. 2/20/2024, Vol. 19 Issue 2, p1-16. 16p.